STUDY OF EFFICACY OF PLATELET RICH PLASMA DRESSING IN MANAGEMENT OF CHRONIC NONHEALING LEG ULCERS

Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 16

Abstract

BACKGROUND Diabetic foot ulcers continue to be a significant global issue despite the advances made in the management of diabetes. It causes major foot complications if they are not addressed properly. It needs multidisciplinary approach for its care. While several advancements have taken place in wound care management, platelet rich plasma and stem cell therapy promise to offer a new hope in its management, aiding in cellular and tissue regeneration. The purpose of the present study was to compare Platelet-Rich Plasma versus conventional dressing in the management of diabetic foot ulcers. METHODS Patients presented with chronic non healing ulcers were recruited in this study. This was a prospective study conducted at Krishna Hospital & Medical Research Centre, Karad. A total of 50 patients was assigned. They were grouped through computerized randomization into two groups. Control group patients were treated with conventional dressing and study group patients were treated with platelet rich plasma (PRP) dressing and observed for reduction in the wound size in a span of 21 days. RESULTS The study group patients showed higher reduction in wound size of about 43.40 % as against 14.03 % in the control group with p value < 0.001. CONCLUSIONS Platelet rich plasma dressing significantly increases incidence of wound healing in chronic lower limb ulcers.

Authors and Affiliations

Kulkarni S. R, Aditya Chawla

Keywords

Related Articles

&nbsp;FNAC OF HIV LYMPHADENOPATHY IN A TERTIARY CARE HOSPITAL: A TWO YEAR STUDY

&nbsp;The incidence of Human Immunodeficiency Virus (HIV) infection is seen to be increasing in Asia, particularly in the Indian subcontinent. Immune system and the central nervous system are the two major targets of...

EVALUATION OF THE EFFECTS OF CAPSULES CONTAINING TRIBULUS TERRESTRIS EXTRACT AND LCARNITINE ON TREATMENT OF OLIGOSPERMIA IN MALES

BACKGROUND Infertility is defined as failure to achieve pregnancy after one year of unprotected sexual intercourse. Male infertility is one of the most challenging problems in andrology. The common cause of male infertil...

&nbsp; CHARACTERIZATION AND ANTIFUNGAL SUSCEPTIBILITY PATTERN OF CANDIDA SPP. ISOLATED FROM CLINICAL SPECIMENS

&nbsp;[b] BACKGROUND[/b]: With the changing health scenario fungal infections have increased significantly, contributing to morbidity, mortality and health care cost. Candida is major human fungal pathogens that cau...

&nbsp;CLINICAL ANALYSIS OF LOW VISION AIDS

&nbsp;[b] AIM[/b]: to clinically analyze 50 cases of low vision patients attending tertiary care hospital, their acceptance of low visual aids and to identify common ocular conditions leading to low vision. [b]METHODS[...

TRAUMATIC CATARACT- AN EPIDEMIOLOGICAL STUDY

BACKGROUND Traumatic cataract is seen in ocular trauma and is one of the leading causes of unilateral blindness in the world. Visual recovery depends on intervention and regular follow-up for a period of 12 weeks. Trauma...

Download PDF file
  • EP ID EP612004
  • DOI 10.14260/jemds/2019/291
  • Views 79
  • Downloads 0

How To Cite

Kulkarni S. R, Aditya Chawla (2019). STUDY OF EFFICACY OF PLATELET RICH PLASMA DRESSING IN MANAGEMENT OF CHRONIC NONHEALING LEG ULCERS. Journal of Evolution of Medical and Dental Sciences, 8(16), 1307-1310. https://europub.co.uk/articles/-A-612004