Study of Electroencephalogram changes in Hypothyroidism
Journal Title: Applied Physiology and Anatomy Digest - Year 2016, Vol 1, Issue 2
Abstract
Hypothyroidism is a common disorder with highly variable presentations; no predictable progression of symptoms is apparent. This study mainly focuses on the effect of hypothyroidism on central nervous system. Aim - The purpose of this study is to study the changes in Electroencephalogram in hypothyroidism, to know the prevalence of background slowing of brain activity on electronencephalogram in patients with hypothyroidism and to correlate mental status changes with electroencephalpogram abnormalities. Study setting and Design - 60 patients with hypothyroidism were examined in outpatient/inpatient in a tertiary care hospital from July 2013 to September 2015. It is a prospective type of study. Written and informed consent were taken in language respondent understand. Data collection was done with the help of detailed examination. Data analysis – Statistical Programme for Social Sciences (SPSS) software 15 version and OpenEpi software version 2.3 were used for data analysis. Results – Out of 60 patients with hypothyroidism, abnormal EEG finding was seen among 12 cases with hypothyroidism. MMSE score and EEG association showed that MMSE score was significantly less among the cases with abnormal EEG. Symptoms like fatigability, difficulty in concentrating, increased sleep and slowing of physical activity were significantly associated with abnormal EEG. Association between T3, T4 and TSH with EEG showed that Mean TSH was significantly raised among the cases with abnormal EEG as compared to normal EEG. Conclusion- Our study showed significant number of Hypothyroid cases having Electroencephalogram changes. TSH was significantly raised among Hypothyroidism cases with abnormal EEG.
Authors and Affiliations
Madhulika Mahashabde
Keywords
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