Study of Endometrial Pathology in Abnormal Uterine Bleeding

Journal Title: International Journal of Biomedical and Advance Research - Year 2017, Vol 8, Issue 2

Abstract

Objectives: To evaluate histopathology of endometrium in patients presenting with abnormal uterine bleeding and to find out the prevalence of various pathological conditions in endometrium in different age groups. Method: Total number of 300 cases clinically presenting with AUB were studied from October 2014 to September 2015. The study included endometrial curettage, biopsy and hysterectomy specimens. Results: Most common histopathological finding was proliferative phase and the most common abnormality detected was retained products of conception in 21- 40 years age group. Most common histopathological finding in 41- 50 years age group was also proliferative phase and the most common abnormality detected was endometrial hyperplasia. In 51- 60 years and >60years age groups, endometrial carcinoma constituted the most common pathology followed by endometrial hyperplasia. Conclusion: Histological examination of the submitted endometrial tissue remains the standard diagnostic procedure for the assessment of AUB. Establishing a cause of AUB is important, as medical therapy is effective in managing abnormal bleeding in most cases and should be attempted before surgical management. Histopathological evaluation of endometrium is especially indicated in women over the age of 35 years to rule out preneoplastic lesions and malignancies.

Authors and Affiliations

Anam Khan, Ruchee Khandelwal, Shashibala Arya, Hema Pant

Keywords

Related Articles

Evaluation of cardioprotective activity of ethanolic extract of dried leaves of Cinnamomum tamala in rats

The present study was designed to scientifically evaluate the cardio protective potential of Ethanolic Extract of dried leaves of Cinnamomum tamala (Family: Lauraceae) (EECT), against doxorubicin induced myocardial infar...

Study of lipid profile in HIV/AIDS patients on antiretroviral therapy

Background: The introduction of effective highly active antiretroviral therapy (HAART) in the mid 1990s lead to the marked reduction in the morbidity and mortality from human immunodeficiency virus (HIV) infection. Incre...

Impact of Acute Lethal and Chronic Sublethal toxicity of Phorate on Succinate Dehydrogenase activity in the Fresh Water Fish Cyprinus carpio

The present study is aimed to investigate the acute and chronic toxicity stress of phorate, induced alterations in the activity levels of Succinate Dehydrogenase (SDH), a vital enzyme of citric acid cycle that catalyses...

Evaluation of endothelial dysfunction in patients with type 2 diabetes mellitus Analysis of 100 cases

Background: Atherosclerosis which is a precursor for macro-vascular disease involves both functional as well as structural changes in the vasculature. Functional changes involve abnormalities in endothelium, vascular smo...

A Study Of Variations In The Origin Of Vertebral Artery And Its Clinical Significance

Objectives: An understanding of anatomy is essential to surgeons and knowledge of variations is of practical importance. The anatomic and morphologic variations of great vessels are significant for diagnostic and surgica...

Download PDF file
  • EP ID EP383696
  • DOI 10.7439/ijbar.v8i2.3916
  • Views 103
  • Downloads 0

How To Cite

Anam Khan, Ruchee Khandelwal, Shashibala Arya, Hema Pant (2017). Study of Endometrial Pathology in Abnormal Uterine Bleeding. International Journal of Biomedical and Advance Research, 8(2), 38-43. https://europub.co.uk/articles/-A-383696