Study of endometrial pathology in perimenopausal women with abnormal uterine bleeding
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2016, Vol 20, Issue 3
Abstract
Context: Abnormal uterine bleeding is one of the most common causes of concern for women in perimenopausal age group. An understanding and recognition of the wide spectrum of normal menstruation, normal cyclical patterns, proliferative lesions, precursor lesions and carcinoma of the endometrium is important. This knowledge is essential for prevention and effective management of these patients. Aim: To analyse the patterns of changes in endometrium in perimenopausal women who presented with abnormal uterine bleeding. Materials and Methods: A total of 3795 cases of formalin fixed and paraffin embedded sections of endometrial tissue was retrieved and reviewed from the Archives of Department of Pathology. All the patients included in the study were perimenopausal women with abnormal uterine bleeding, the age ranging from 40years to 55years from Jan 2008 to Dec 2012. The study consisted of 1880 endometrial biopsies which included endometrial curettings and aspirates and 1915 surgically resected hysterectomy specimens. 161 specimens were excluded from the study due to inadequate sampling. Results: Our study showed that abnormal uterine bleeding was seen often between 40-45yrs of age. The Incidence of Perimenopausal women with Abnormal Uterine bleeding decreased with age. The incidence was significantly low above the age of 51 years (13.40%). In perimenopausal women with abnormal uterine bleeding 42.8% had normal cyclical pattern, 32.1% had disordered proliferative pattern. Less than 5% of this population had hyperplasia or carcinoma.
Authors and Affiliations
Divya D, J Thanka, Pavithra V
Keywords
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