Study of etiologic factors for optic atrophy
Journal Title: Офтальмологический журнал - Year 2019, Vol 0, Issue 2
Abstract
Background: Optic atrophy (OA) is a disease of multiple etiologies and is a consequence of various pathological changes along the optic pathway. Central nervous system (CNS) disorders, vascular impairments and retinal and optic nerve diseases are important in the etiology of this condition. Purpose: To investigate various etiologic factors for OA. Materials and Methods: Patients were retrospectively divided into three groups: Group 1 (primary descending OA; 2,046 patients); Group 2 (primary ascending OA; 430 patients); and Group 3 (secondary OA; 190 patients). Results: Supratentorial tumors prevailed (78.0-79.4%) among the neurosurgical disease causing optic atrophy. Vascular factor was the most common cause (27.6-28.5%) of ascending OA, followed by inflammatory (25.5-30.1%). We found the presence of essential hypertension, diabetes mellitus type 2, and atherosclerosis to be significant medical risk factors for OA, with odds ratios of 2.46 (95% CI = 1.69 to 3.58), 2.32 (95% CI = 1.22 to 4.41), and 2.11 (95% CI = 1.41 to 3.15), respectively.
Authors and Affiliations
V. Vasyuta, Yu. Pedachenko
Keywords
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- EP ID EP586858
- DOI 10.31288/oftalmolzh201924449
- Views 69
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