Study of Fibrinogen Level in Type 2 Diabetes and Its Influence on Peripheral Arterial Disease
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2018, Vol 4, Issue 12
Abstract
A study on the level of fibrinogen in Type 2 Diabetes patients and its influence on Peripheral Arterial Disease. Three groups (Group A- Diabetes patients, Group B- patients with DM+PAD, control group of healthy volunteers) of patients were included. Plasma fibrinogen level of all the patients were measured and is correlated with age, sex, BMI, WHR, HbA1C, FBS and ABI of the patients. PAD patients were identified with the help of ABI measurement. PAD is an expression of systematic atherosclerotic disease, if it is not diagnosed in the early stage it will lead to serious complications like Myocardial infarction, stroke and death. Role of haemostatic factors particularly Fibrinogen in vascular disorders has gained considerable interest. Comparatively increased fibrinogen concentration was seen in patients with both DM and PAD (414.97±28.73). We have also found that fibrinogen is increased in some diabetic patients with poor glycaemic control. This elevated fibrinogen can be considered as an indicator for cardiovascular disorders in diabetic patients. These results underline the possible relation between fibrinogen and presence of PAD in diabetic patients and thus the study reflects the importance of proper maintenance of glycaemic status in Diabetic patients.
Authors and Affiliations
Narmadha MP, Arun S. Menon, Anusree M. S
Keywords
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