Study of fine needle aspiration cytology in the diagnosis of ovarian masses
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2016, Vol 21, Issue 1
Abstract
Background: Earlier the technique of aspirating ovarian masses was mostly unguided imaging technique. The ovarian masses were located by palpation and were approached transrectally, transvaginally and transcutaneously for fine needle aspiration cytology. The advancement of imaging technique has enabled many workers to undertake fine needle aspiration cytology of ovarian masses as it helped in correct localization and sampling from suspected area of cancerous and noncancerous lesions. Objectives: To study cytomorphological features of benign and malignant conditions of ovarian masses obtained at ultrasound guided fine needle aspiration cytology. To determine sensitivity and specificity at ultrasound guided fine needle aspiration cytology in diagnosis of ovarian masses. To draw value of comparison between cytodiagnosis and histomorphological diagnosis; rate of accuracy, false positive, false negative, positive predictive value and negative predictive value. Material and Methods: The present prospective study was carried out in the Department of Pathology, Jawaharlal Nehru Medical College, Sawangi (M), Wardha during two years duration from July 2009 to June 2011.FNAC was performed on cases with suspected ovarian masses with plan for surgical treatment. The material obtained at aspiration was wet fixed in 95 % ethyl alcohol and stained with papanicolaou stain while few were dry fixed and stained with May Grunwald Giemsa stain. Result: The false positive rate was 0 and false negative rate was 4.34%. The sensitivity and specificity of FNAC in diagnosis of ovarian masses was found to be 95.65% and 100% respectively. Negative predictive value was 96.77% and positive predictive value was 100% of FNAC in diagnosis of ovarian masses. Overall rate of accuracy of FNAC in diagnosis of ovarian masses was 98.11% in present study. Conclusion: FNAC over lesion of ovary carried out under USG guidance is a safe preoperative diagnostic modality. USG guided FNAC in the ovarian lumps has a definite ability to distinguish between a non neoplastic and neoplastic lesions of ovary with confidence.
Authors and Affiliations
Delux V Godghate, Arvind Bhake
Keywords
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