Study of Frequency of Various Clinical Forms of Neonatal Cholestasis in Jharkhand: A Hospital Based Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Backkground: Neonatal Cholestasis occurs due to so many causes like- genetic, metabolic, obstructive & less commonly infective. It is never physiological. Aims & Objectives: To describe a stepwise approach for the evaluation of neonatal cholestasis, to understand the importance of early screening for neonatal cholestasis and to understand the frequency of various clinical forms of neonatal cholestasis. Methodology: It is a prospective cohort study, it will include 30 babies diagnosed as having Neonatal Cholestasis at Rajendra Institute of Medical Sciences, Ranchi, Jharkhand from 13 April 2018 to 31 January 2019. In this study descriptive and inferential statistical analysis of data will be done using suitable stastical method. Results: Of the 30 infants investigated, 12 diagnosed as Biliary atresia(40%), 4 with Progressive familial intrahepatic cholestasis(13%), 3 with Premature delivery(10%), 3 with Infectious diseases(10%), 2 with Metabolic & Endocrine disorders(7%), 1 with Alagille syndrome(3%) & 5 cases are Idiopathic neonatal hepatits(17%). Conclusion: Biliary atresia is the most common entity leading to Neonatal cholestasis,It must be differentiated from other causes of cholestasis (PFIC , Infectious diseases,premature delivery, Metabolic & Endocrine disorders and Idiopathic neonatal hepatits) promptly because early surgical intervention before 2 months of age results in a better patient outcome.
Authors and Affiliations
Dr. U. P. Sahu, Dr. (Prof. ) A. K. Chaudhary, Dr. Gora Chand
Keywords
Related Articles
- EP ID EP557483
- DOI 10.9790/0853-1803127883.
- Views 78
- Downloads 0
Effects of Different types of Pica substances on Maternal and Fetal Outcome- A prospective study
The present study was carried out to study effects of different types of pica substances on maternal and fetal outcome. Of total 150 pregnant women were studied, 6.7% of the subjects reported to have pica. The prevalence...
Temporomandibular Disorders its Signs and Symptoms and Prevalence in Dental Students
Aim and Objective: The objective of this study was to investigate the prevalence of signs and symptoms of temporomandibular disorders (TMDs) in dental students. Materials and methods: A total of 100 dental students, at P...
To Study Level of Serum Cortisol and Prolactin in Diabetic Retinopathy
Diabetic retinopathy refers to retinal changes seen in patients with diabetes mellitus.Degree of cortisol secretion is related to the presence and number of diabetic complications(Diabetes care 30:83- 88,2007).The hormon...
Outcome of Management of Diaphragmatic Hernia; Review of Three Year Experience
Diaphragmatic hernia (cdh) is a defect in the dome of diaphragm, more often in left and postero-lateral that permits the herniation of abdominal contents into the thorax. The lungs hypoplasia, pulmonary hypertension and...
A Comparative Physicochemical & Phytochemical Study of Leaves, Roots and Stem Barks of Bruhatpanchamoola (A Group of Five Perennial Plants)
Bruhatpanchmoola is a ayurvedic formulation of five perennial plants roots i.e. Bilva {Aegle marmelos (L.) Corr.}, Gambhari (Gmelina arborea(L).), Agnimanth (Clerodendrum phlomoidisL.f.), Shyonaka {Oroxylum indicum(L.) V...