Study of Health Related Quality Of Life in Patients with Gastro esophageal Reflux Disease

Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 4

Abstract

Background: Gastro esophageal reflux disease (GERD) is a common problem worldwide with a wide range of clinical manifestations and potential complications like esophagitis, ulceration and stricture formation. It is a common disorder associated with substantial reduction in health related quality of life. Objective: To assess the health related quality of life in GERD patients. Methodology: The study was conducted at Gastroenterology department (outpatient and inpatient) of St Joseph General Hospital, Guntur. The study was a prospective interventional observational study conducted over a period of six months from December 2017 till April 2018. Patients satisfying the study criteria were enrolled into the study after obtaining an informed consent. The enrolled patients were interviewed and their medical records were reviewed to record information about their demographic variables, level of education, social habits, diagnosis, current and past medical and medication history. Patients Health Related Quality of life was assessed using SF12 questionnaire at the baseline. The patients were then counseled in a private area to ensure privacy and provided with education about GERD. The patients were followed up for 30 days and their HRQOL was re-assessed using SF12 Questionnaire and their scores were calculated and outcome was measured to assess improvement in HRQOL. Results: A total of 80 patients were included in the study. 15 patients (13.07%) were considered as drop outs due to irregularity in follow up. Of the 80 patients who completed the follow up and considered for study, preference existed for the gender and GERD was found to be more prevalent among the males [n=54(67.5%)] then in females [n=26(32.5%)]. In the study it was found that GERD occurred in all age groups with an average age of 44 years. Physical Composite Score (PCS) of the patients were found to be 34.96 and most of the patients distributed in the mean range of 30 to 35 years. In the follow up after providing education for the patient about disease and lifestyle modifications the mean score of the patient increased (46.9). The Mental composite score ( MCS) score was also found to be higher compared to baseline among the patients after counseling (from 40.5 to 53) . Conclusion: This study has helped to identify and track unmet health needs and disparities. The complete resolution of symptoms were not observed since the patients were followed up for only 4 weeks but improvement in their quality of life were seen. This study concludes that improving patient knowledge about GERD by providing patient education can improve their overall health related quality of life.

Authors and Affiliations

Dr. Krishna Pavan Kumar J, K Bindu Madhuri, B Prasanthi, Dr Shaik Faizan Ali, Mr G Sada Sivarao, Mr V D C Sravan Kumar, Dr Konda Ravi Kumar

Keywords

Related Articles

Design and Characterization of Effervescent Gastro Retentive Floating Tablets by Using Venlafaxine Hcl as a Model Drug

In the present research work the gastro retentive floating matrix formulation of Venlaflaxine hydrochloride by using various hydrophillic polymers. Initially analytical method development was done for the drug molecule....

Microbial quality assessment of an abattoir effluent discharged into Waterside Riverin Aba, Abia State, Nigeria

The microbial quality of an abattoir effluent discharged into Waterside River in Abawas investigated. Samples were taken from the abattoir effluent, and from upstream and downstream of the receiving water body, and were...

Assessment of Airborne Fungi in an Indoors Laboratory Toilet

Fungi are ubiquitous in both indoors and outdoors environment, exposures to them result to allergies, infection and other adverse health conditions. The assessment of indoor fungi prevalent in six toilets (Biotechnology...

Quantized Mitochondrial Metabolism

Mitochondrial biology is a rapidly growing sector, attracting the attention of many researchers. In particular, research on processes related to reactive oxygen species (ROS) and understanding of the risks associated wit...

The Effects of Pilocarpine Mouthwash on Vocal Quality

Objective: to verify the effects of pilocarpine mouthwash on vocal acoustic parameters and salivation of healthy volunteers. Method: a clinical, randomized, placebo-controlled (saline) trial was conducted with 36 healthy...

Download PDF file
  • EP ID EP395549
  • DOI 10.9790/3008-1304037075
  • Views 63
  • Downloads 0

How To Cite

Dr. Krishna Pavan Kumar J, K Bindu Madhuri, B Prasanthi, Dr Shaik Faizan Ali, Mr G Sada Sivarao, Mr V D C Sravan Kumar, Dr Konda Ravi Kumar (2018). Study of Health Related Quality Of Life in Patients with Gastro esophageal Reflux Disease. IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS), 13(4), 70-75. https://europub.co.uk/articles/-A-395549