Study of incidence of varied etiology of first episode Pediatric Seizures and its correlation with EEG and Neuroimaging
Journal Title: Perspectives In Medical Research - Year 2019, Vol 7, Issue 1
Abstract
Objective: To determine correlation between clinical features, EEG findings and neuroimaging (Magnetic Resonance Imaging) abnormalities in children with first seizure episode. Materials and Methods :It is prospective study carried out from January 2017 to January2018. 74 children aged between six month to fifteen years with first seizure episode admitted in Pediatric Department of Prathima Institute of Medical Sciences were enrolled and detailed history and investigations including MRI,CT and EEG were done .Children with Neonatal seizures,Previous episodes of seizures, stroke in young, poisonings,malingering,pseudo seizures were excluded from the study. Results:: We investigated 6 months to 15-year-old children with first episode of seizure. Seventy four children were enrolled for investigation. There were 32 (43.3%) girls and 42 (56.7%) boys. 54 (66%) children had abnormal electroencephalography (EEG) and 35 of them had generalized epileptiform discharges and 19 had focal epileptiform discharges . Abnormal MRI was seen in 48 (64.8%) patients and consisted ring enhancing lesion ( Neurocysticercosis and Tuberculomas),bilateral thalamic hypodensities,atrophy& gliosis, periventricular leucomalacia. Abnormal MRI findings had significant relation with abnormal EEG, age, positive family history for epilepsy, nutritional status,socio economic group,electrolyte abnormalities . Statistically significant correlation found between MRI and EEG findings. Statistically significant correlation found between seizures and abnormal birth history, delayed development milestones, fever at the time of presentation, hypoglycemia, low socioeconomic status. Conclusion:In children with abnormal EEG, neuroimaging should be considered. We suggest to use EEG for confirmation of epilepsy and perform MRI for patient with abnormal physical exams, focal neurologic deficits or focal EEG abnormalities.
Authors and Affiliations
Sandeep Reddy Ch
Keywords
Related Articles
- EP ID EP391554
- DOI -
- Views 130
- Downloads 0
Emergency peripartum hysterectomy: A three year experience at a tertiary care center
Introduction: Emergency peripartum hysterectomy (EPH) is a major surgical procedure performed for life threatening obstetrical hemorrhage, during or immediately after abdominal and vaginal deliveries. It is considered as...
Comparative evolution of serological tests in the diagnosis of Syphilis
Background: Diagnostic and therapeutic approaches in syphilis show wide variation. The use of only one type of serologic test is insufficient for diagnosis. Objective :The aim of the study was to review serologic data...
Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease
Introduction: Tuberculosis is one of the most prevalent bacterial infection in developing country like india and it is capable of affecting almost every system in the human body. Multifocal skeletal tuberculosis is a rar...
Clinicopathological study of Ovarian tumours
Introduction: The ovary consists of sex cells, which are totipotential and of mesenchymal cells which are multipotential.So when it becomes neoplastic almost any type of tumour can result. The ovarian tumours manifest as...
Standard statistical methods and calculation of sample size in Medical education research
Introduction: After confirmation of any line and area of Research work, the Basic Question starts with Collection of Sample size determination, but before that in a health science research "why statistical methods are so...