Study of Left Ventricular Mass and Its Determinants on Echocardiography
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 9
Abstract
Introduction: Increased Left Ventricular Mass (LVM) is an independent risk factor for cardiovascular morbidity and mortality. Aim: This study was done to find the prevalence and determinants of LVM in the Northern Indian population. Materials and Methods: A prospective cross-sectional observational study was carried out in a tertiary care centre in Himachal Pradesh, India and the study population included all consecutive patients fulfilling the inclusion criteria attending cardiology OPD on seeking medical attention with various symptoms for dyslipidaemia, hypertension but not on medication over a period of one year. Focused history was taken; physical examination and investigations were done. Data collected was analysed using Epi-info software version 3.5.1. We calculated means of LVM index for categorical variables i.e., sex, tobacco consumption, alcohol consumption and sedentary lifestyle etc., and also calculated p-values as test of significance for mean difference across the exposure variable groups. The Pearson correlation coefficient was calculated and 2 tailed significance at p< 0.05 was taken as statistically significant. Results: Mean age of study population was 42.30±9.8 years and 62.9% were males. The mean LVM index was significantly higher in men than in women 77.7 ± 11.4 vs.71.3 ± 15.7 (p-value <0.01). Strong positive correlation was observed between increased waist hip ratio and increased Left Ventricular Mass Index (LVMI). The Pearson correlation coefficient was 36.77 and it was statistically significant with p-value 0.04. Conclusion: We found positive and independent correlation of increased LVMI with increased Waist Hip Ratio (WHR). A positive independent correlation was also observed with higher fasting blood sugar levels.
Authors and Affiliations
Namrata Guleri, Susheela Rana, Randhir S Chauhan, Prakash Chand Negi, Yogesh Diwan
Emergency Peripartum Hysterectomy: A 14-Year Experience at a Tertiary Care Centre in India
Introduction: Emergency Peripartum Hysterectomy (EPH), although relatively infrequent in present day obstetrics, is a life-saving procedure in the event of a massive postpartum haemorrhage. Aim: To assess incidence, risk...
VEGF Expression to Support Targeted Therapy in Ovarian Surface Epithelial Neoplasms
Introduction: Vascular Endothelial Growth Factor (VEGF), a promoter of angiogenesis, is a promising target for antiangiogenic therapy in ovarian cancer. In our study, we examined the expression of VEGF in the spectrum of...
Increased Advanced Oxidation Protein Products Generation by Cyclosporine-A and Angiotensin II in Human Gingival Fibroblasts – Ex-vivo Study
Introduction: Cyclosporin-A (CsA), an immunosuppressant, induces renal fibrosis and Renin Angiotensin System (RAS) is known to play a major role. CsA has the potential to increase the oxidative stress; specifically throu...
Massive Benign Phyllodes Tumour of Breast Complicating Pregnancy
Phyllodes tumour of the breast, earlier called cystosarcomaphyllodes, is a rare fibroepithelial breast neoplasm that occurs in all age groups from adolescents to elderly. Phyllodes tumour occurring during pregnancy and a...
Laparoscopic Vesico-Psoas Boari Flap and Ureteroneocystostomy: A Case Report
Ureteric injury, a devastating complication of laparoscopic gynaecological surgery, is often managed by endoscopic stent placement. Failure of endoscopic correction will require laparoscopic or open surgical correction t...