Study of Lipid Profile in Chronic Kidney Disease: A Cross Sectional Study
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 3
Abstract
Introduction: Lipid abnormalities are very common in chronic kidney disease contributing to high incidence of premature atherosclerosis and cardiovascular diseases in such patients. Deaths due to cardiovascular complications are 4-20 fold higher in CKD patients than any other cause in general population. In the course of CKD, lipoprotein disturbances vary significantly depending on the stage of the disease. So, the present study is undertaken to study lipid profile of cases of in chronic kidney disease. Material and method: This cross-sectional study was conducted in Indira Gandhi Government Medical College and Hospital, Nagpur. 100 diagnosed chronic kidney disease patients attending medicine outpatient department (OPD) and/or admitted in ward/kidney unit in this institute were enrolled for the study. Cases were divided in five stages of disease based on the Glomerular Filtration Rate. All the cases were investigated for kidney function test and lipid profile. Result: Mean age of study subject was 47.49 ± 11.70 years, ranging from 21 to 65 years. Male study subjects were 59 %. Diabetes Mellitus was the main aetiology of CKD followed by Hypertension. Mean triglyceride was 217.4 ± 44.11 and mean VLDL cholesterol was 44.37 ± 8.99. Conclusion: Mean serum creatinine and blood urea values increases as the stage of CKD increases in study subjects (p=0.000). Mean triglyceride and VLDL cholesterol level increases as the stage of CKD increases from stage I to stage V (p=0.000).
Authors and Affiliations
Dr Ashok Jadhao
Keywords
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