Study of Meningioma at a tertiary care center, Gwalior: A five Year study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 10
Abstract
Background:-Meningiomas are most common benign neoplasm of central nervous system that arises from meningial arachnoid cells of brain and spinal cord. Meningiomas are slow growing tumor with slightly female predominance because of its association with progesterone receptor. Histological differentiation of meningioma has a great prognostic implication. Aim: - Aim of the study is to evaluate the different histological variant of meningiomas and its prevalence at a tertiary care center, G. R. Medical College Gwalior, Madhya Pradesh. Material and methods: - This is a 5 year retrospective and prospective cohort study of meningioma from January 2013 to December 2017. In this study, received 117 histological specimens from neurosurgery department of G R Medical College were processed for histo-pathological examination and reporting. The data was collected, retrieved, tabulated, summarized and compared statistically by frequency distribution and percentage Proportion. Chi-square (X2) test was applied to evaluate the significant (p-value) ratio of difference statistically Result: - In the present study the most common variant of meningioma was meningothelial meningioma and most common age group was 41- 50 year. According to WHO grading frequency of meningioma was; Grade I meningioma 94.89% while grade II 1.70% and grade III were 3.41% in our study. Male to female ratio was 47:53%. Conclusion: - In our study of 117 cases, meningothelial meningioma was the most common histomorphological variant of meningioma while according to WHO grading of meningiomas, 94.89% were belongs to grade I meningioma and rest grade II (atypical) 1.70% and grade III (anaplastic) meningiomas contributed 3.41%
Authors and Affiliations
Dr Sudha Iyengar, Dr Ajay Patel, Dr Dharmesh Chandra Sharma, Dr Rashmi Samele, Dr Devendra Singh Rajawat, Dr Bharat Jain
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