Study of microalbuminuria and its correlation with glycaemic status in type 2 diabetes mellitus
Journal Title: MRIMS Journal of Health Sciences - Year 2016, Vol 4, Issue 4
Abstract
Background: It is well established that diabetic nephropathy is a dreaded complication of Type 2 diabetes mellitus. However in the early stages; also known as incipient nephropathy, it can be detected by the presence of microalbuminuria. If the patient is identified in the incipient nephropathy stage itself, effective control measures can be initiated to retard the progression to end stage renal disease. Objective: To know the occurrence of microalbuminuria in patients with Type 2 diabetes mellitus and to correlate it with the glycaemic status of the patients. Methods: This study was undertaken in NRI Medical College and General Hospital, Chinakakani, Guntur District, Andhra Pradesh from Nov. 2010 to August 2012. A total of one hundred randomly selected diabetic patients satisfying the inclusion criteria were selected for the study. All patients were evaluated in detail along with the testing for microalbuminuria with dipsticks (Micral) and their glycaemic status along with other required parameters. Results: The overall occurrence of microalbuminuria in the test series was 38%. The occurrence of microalbuminuria showed a direct relationship with the poor glycemic status (p=0.053) and increasing duration of diabetes since diagnosis (p<0.001). An HbA1c value above 7% is associated with 50% or higher incidence of microalbuminuria (p=0.018). Patients with a body mass index of more than 25 kg/m2 have a significant increase in the incidence of microalbuminuria (p=0.027). The incidence of microalbuminuria is significantly associated with the presence of retinopathy (p=0.073), peripheral neuropathy (p=0.009), ischemic heart disease (p=0.011) and hypertension (p=0.001). Microalbuminuria is inversely associated with HDL (p= 0.089). Conclusion: The occurrence of microalbuminuria in Type 2 diabetic patients in the study was quite high and more so in patients with poor glycemic control.
Authors and Affiliations
Srjana K, Amith Kumar P
Maternal and Child factors associated with Neonatal jaundice influencing the outcome of Phototherapy in Karimnagar district
Background: Neonatal jaundice became a pediatric emergency in all the populations. Though it was usually managed by phototherapy consideration of its maternal and child causes was a better choice for its prevention, Obj...
A study of Clinical Profile of patients with Dengue fever
Background: Dengue fever with estimated 50-100 million infections and 2,00,000 – 500000 cases of DHP per year. Case fatality rate is around 5%. 4 So early diagnosis and initiation of treatment of Dengue fever prevents mo...
A retrospective epidemiological study of human rabies cases admitted in Sir Ronald Ross Institute of Tropical and Communicable Diseases
Rabies is one of the deadliest diseases known to man; it remains a neglected zoonotic disease throughout the developing countries. Rabies is an acute condition, 100% fatal and it is transmitted to humans through animal...
A study of effect of iron on hematological status in iron deficiency anemic children
Background: Iron Deficiency is the most widely prevalent nutritional disorder affecting the world population today. Anaemia has been described as a major health problem in the developing countries. Iron Deficiency Anaemi...
Competency and satisfaction level of high and medium fidelity simulation in drug administration teaching and learning practice: A comparative study
Background: Nowadays, the simulation practice is becoming more popular in nursing education and that can improve the nursing students’ clinical skills and soft skills. Moreover, it allows the students from conductive sim...