Study of Morphological and Histopathological Changes in Placenta in Preeclampsia and its Association with Maternal and Fetal Outcome
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 10
Abstract
Hypertensive disorders in pregnancy forms one part of the deadly triad, along with haemorrhage and infection that contribute greatly to maternal and fetal morbidity and mortality. Careful examination of placenta can give information that may be important in the immediate and later management of mother and infant. Microscopic examination of the placenta is important to determine the nature of the pathology, but many disorders show similar features. The study was done in 100 placentas, out of the 100 placentas collected, 50 placentas from uncomplicated full term normal deliveries and another 50 were collected from pre-eclamptic patients. Gross and microscopic examination of the placenta was carried out. The size, shape, weight, thickness at centre, number of cotyledons, and site of insertion of umbilical cord was noted. Pre-eclampsia (PIH) significantly affects the placenta by reducing its weight and dimensions.. It induces histological changes such as, areas of syncytial knot formation, fibrinoid necrosis, calcified areas, hyalinised areas, and areas of medial coat proliferation of the blood vessels.
Authors and Affiliations
Dr. Ashish Tale, Dr. Gautam S Aher, Dr. Urmila Shinde, Dr. Suhas Shinde
Keywords
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