Study of Mucin Histochemistry in Chronic Calculous Cholecysttits.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Disorders of the biliary tract affect a significant portion of the world’s population. Over 95% of the biliary tract disease is attributable to cholelithiasis.Gall stones afflict 10 to 20% of adult opulation in developed countries necessitating hospitalization and cholecystectomy. The bile content play crucial role in the formation of gallstones. Gall bladder secretes mucin which is a high molecular weight glycoprotein. . Gallbladder mucin shares with other epithelial mucins the ability to bind lipids and bile pigment. This gallbladder mucin has long been recognized as an important factor contributing to initiation and formation of gall stones .Many studie have been done to see if there is any relationship between pathological changes in diseased gall bladder and gall stones formation. This study has been taken to see the histochemical alterations of mucin expressed in diseases gall bladder epithelium ,in cases of cholecystectomy done for chronic calculous cholecystitis .An attempt has also been made to correlate type of mucin expressed with histopathological features of chronic cholecystitis like inflammation and fibrosis.
Authors and Affiliations
Dr. V. Dhamodharan Md, Dr. Vindu Srivastava
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