STUDY OF NEW POLYMER FORMS OF INTERFERON INDUCTOR WITH ANTI-VIRAL ACTIVITY
Journal Title: International scientific journal Science and Innovation - Year 2024, Vol 3, Issue 6
Abstract
This article examines the possibility of obtaining a polymer form of new preparations of interferon inducers based on carboxymethylcellulose dialdehyde and gossypol. By chemically combining the dialdehyde of water-soluble carboxymethylcellulose with the natural polyphenol gossypol, water-soluble polymer derivatives of gossypol with interferon-inducing and antiviral properties were obtained. Water-soluble, purified Na-carboxymethylcellulose (Na-CMC) with a degree of polymerization DP=650±20 and a degree of substitution DS=0.85±3 were selected as research objects. The physico-chemical and medico-biological properties of a new antiviral drug against viral influenza and ARVI were studied. The optimal ratios of components were selected to obtain the polymer form of the antiviral drug.
Authors and Affiliations
Azizova M. A. , Karabaeva B. S. , Sarymsakov A. A.
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