Study of oxidants and antioxidants in subtypes of female infertility in blood samples
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2016, Vol 21, Issue 2
Abstract
Background: numerous studies have shown the role of oxidative stress in male factor infertility. The aim of present study is to evaluate the role of oxidative stress in female infertility again in various subtypes of female infertilities. Materials and Methods: oxidative stress parameters like Nitric oxide and Malonaldehyde were assayed as oxidants whereas Superoxide dismutase, reduced glutathione and Vitamin E were assayed as antioxidants both in blood. Statistical analysis was performed using Z test and One Way ANOVA. Result: Oxidants Nitric oxide and Malonaldehyde showed increase in blood. On the other hand antioxidants Superoxide dismutase, reduced glutathione and vitamin E showed decrease in blood. Conclusion: our approach clearly indicates that oxidative stress can be one of the major factors affecting fertility in females. As oxidative stress was present in many subtypes of infertility, it can be one of the factor responsible for causing tissue damages in related conditions like endometriosis,tubal factor etc.
Authors and Affiliations
Ashwini Kamble, Kanchan Mohod, Satish Kumar
Keywords
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