Study of Oxidative Stress and Antioxidants in Chronic Migraine
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 5
Abstract
Migraine is the most common neurological disorder; on molecular basis it is still not completely understood. An impairment of mitochondrial oxidative metabolism might play a role in the pathophysiology. The aim of this present study was to investigate the differences in oxidative stress status with the measurement of glutathione reductase (GR), glutathione peroxidase (GPx), Superoxide dismutase (SOD), glutathione -s- transferase (GST) and total antioxidant (TAS). There were 110 patients selected in the migraine group and 50 age matched healthy subjects were selected in control group. It shows that the levels of GR, GPx, GST, SOD and total antioxidant were significantly decreased found in migraine patients before treatment compare to normal group as well as after treatment.
Authors and Affiliations
Dr Pradeep Kumar Shukla
Keywords
Related Articles
- EP ID EP515797
- DOI -
- Views 48
- Downloads 0
Study of the Baseline Widal Titres among Healthy Population in a Tertiary Care Hospital in Central India
Background: In developing countries like India, Enteric fever is endemic. Widal agglutination test is used for its diagnosis. In a single serum sample the only test frequently relied upon for laboratory diagnosis is Wida...
To Study Clinical Profile of Coronary Artery Disease in Rural Patients and Its Comparison with Urban Patients
Background: Coronary artery disease (CAD) is one of the most common cause of mortality and morbidity in both developed and developing countries. The rural-urban differences in the prevalence of CAD indicate that differen...
Gleason’s Grading of Carcinoma Prostate with PSA Correlation
Introduction: Serum PSA levels have been linked directly to a number of important prognosticators in the prostate gland including histologic grade. The present study has been undertaken on cases of carcinoma prostate, wh...
Yellow Eyed Man with a Stone in the Pouch
Mirizzi Syndrome is a rare complication of gallstone disease which is always caused by a calculus in the cystic duct or neck of the gallbladder, resulting in mechanical compression of common bile duct and the gallbladder...
Clinical Study of Fistula in Ano
Fistula in ano forms a good majority of treatable benign lesions of the rectum and anal canal. 90% or so of these cases are as a result of cryptoglandular infections. As such, the vast majority of these infections are ac...