Study of Oxidative Stress and Antioxidants in Chronic Migraine
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 5
Abstract
Migraine is the most common neurological disorder; on molecular basis it is still not completely understood. An impairment of mitochondrial oxidative metabolism might play a role in the pathophysiology. The aim of this present study was to investigate the differences in oxidative stress status with the measurement of glutathione reductase (GR), glutathione peroxidase (GPx), Superoxide dismutase (SOD), glutathione -s- transferase (GST) and total antioxidant (TAS). There were 110 patients selected in the migraine group and 50 age matched healthy subjects were selected in control group. It shows that the levels of GR, GPx, GST, SOD and total antioxidant were significantly decreased found in migraine patients before treatment compare to normal group as well as after treatment.
Authors and Affiliations
Dr Pradeep Kumar Shukla
Keywords
Related Articles
- EP ID EP515797
- DOI -
- Views 56
- Downloads 0
Pheochromocytoma: Presenting As Urinary Tract Infections
Pheochromocytoma are rare, catecholamine secreting neuroendocrine tumour of adrenal medulla [1] . We present a case of an 80 year old male complaining of recurrent urinary tract infection diagnosed as pheochromocytoma on...
Assessment of Quality of Life, Depression, Anxiety and Suicidal Tendencies in Patients with Epilepsy: A Hospital Based Study
Epilepsy is generally associated with decrease in the quality of life of patients, it causes depression, anxiety and suicidal tendencies in patients. We are conducting this study to test whether the patients are having t...
Bilateral Primary Ovarian Hydatid Cysts – A Rare Occurence
Primary ovarian hydatid cyst involving bilateral ovaries is an exceedingly rare occurrence. Involvement of the ovaries in hydatid disease is often secondaryin nature as a consequence of peritoneal dissemination /lymphati...
In Vitro Antioxidant Activity of Methanolic Leaf Extract of Tridax Procumbens and Tithonia Diversifolia
Objective: To analyze the antioxidant activities of the methanolic leaf extract of Tridax procumbens and Tithonia diversifolia. Methods: This was done using various antioxidant models; 1,1-diphenyl-2-picryl hydroxyl (DPP...
Retrospective Study: Micro and Macrovascular Complications in Type 2 D.M in Tertiary Care Hospital
Diabetes is one of the most common endocrine disorders. Its disorder of metabolism of carbohydrate , protein and fat due to absolute or relative deficiency of insulin secretion and with varying degree of insulin resistan...