Study of Pattern of Thyroid Dysfunction in Patients with Type 2 Diabetes Mellitus in a Rural Hospital in Karnataka
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Background and Objectives: Thyroid dysfunction is known to occur in patients with Type 1 DM, It is due to autoimmunity. The prevalence of thyroid dysfunction in patients with Type 2 DM varies between 10% - 31%. Subclinical hypothyroidism andovert hypothyroidism is the pattern commonly observed. Altered thyroid functions is associated with deranged fat metabolism. The deleterious effects on lipid profile inturn leads to adverse cardiovascular and cerebrovascular events. Hence this study aims at studying the prevalence and pattern of thyroid dysfunction in patients with Type 2 DM. Materials and Methods: This is aprospective case control study conducted in Adichunchanagiri Institute of Medical Sciences,B .G .Nagar, Nagamangala Taluk. It is situated in a rural place and predominantly serves a large village population.Out of 108 patients studied 54 were cases and 54 controls. Patients with pre existing thyroid dysfunction or on medications that alter thyroid dysfunction, pre existing liver / renal disease, pregnant women were excluded from study. Informed consent was taken. Detail history and physical examination were done. FBS, PPBS, HbA1c, Serum Creatinine, Fasting Lipid Profile and Thyroid Profile were done.fT4 if required. Results: There were 21 (38.8%) males and 33 (61.2%) females in cases and 15 (27.7%) males and 39 ( 72.3%) females in controls. In cases 19 (35.2%) patients had thyroid dysfunction. 13 (24.1%) had subclinical hypothyroidism and 6 (11.1%) had overt hypothyroidism. 4 (7.5%) people in control group had thyroid dysfunction. Conclusion: Our study shows that the prevalence of thyroid dysfunction is more in patients with type 2 DM as compared to normal population.
Authors and Affiliations
DrRamanathShenoy B, DrSumanth B V, DrManojkumar B K
Keywords
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- EP ID EP374719
- DOI 10.9790/0853-1705075355.
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