Study of Prevalence of HPV Genome and Detection of Cervical Abnormalities Using Liquid Based Cytologyin HIV Positive Women
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Background :Cervical cancer is the second most common cancer among women worldwide. Infection with the Human Immunodeficiency Virus (HIV) and its related immunosuppression are associated with an increased risk of prevalence, incidence and persistent squamous intraepithelial lesions(SILs) of the cervix. Objectives : (1)To study the changes in cervical cytology with relation to HPV DNA type detected by using RTPCR in HIV positive females. (2) To find out the prevalence of cervical abnormalities in the study group comprising of 100 HIV positive women and 100 HIV negative women as a control. Material and MethodsThe present study was conducted in the department of Pathology, GMC, Patiala on 100 cervical brushings prepared from HIV positive patients attending ART Centre at GMC and hospital, Patiala and 100 cervical brushings prepared from HIV negative women as a control which were prepared in the department of Obstetrics and Gynaecology, Rajindra Hospital, Patiala. The cervical brushings were analysed in the Department of Pathology, Government Medical College Patiala. Liquid based cytology and HPV detection was done on samples of cervical brushings.
Authors and Affiliations
Dr. Surinder Kaur, Dr. Navneet Kaur, Dr. R. K Kundal, Dr. Manjeet Kaur, Dr. Medhavi Dhir, Dr. Ramanpreet Kaur
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