Study of Prevalence of Multi-Drug Resistant Tuberculosis in a Tertiary Care Hospital
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 1
Abstract
Pulmonary tuberculosis with multi-drug resistant Mycobacterium tuberculosis is a major cause of concern in many of the developing countries. The present study was carried out to study the prevalence of multi-drug resistant tuberculosis (MDR-TB) in clinical isolates at DR.PSIMS & RF general hospital in Gannavaram, which is a tertiary care hospital. Two hundred and fifty seven sputum samples were collected from clinically suspected cases of tuberculosis and subjected to Zeihl-Neelsen stains(ZN) and culture on Lowenstein-Jensen(LJ) medium and 50 cultural isolates were obtained and subjected to economic variant of proportion method for drug susceptibility against Isoniazid (INH) and Rifampicin(RIF). A total of eight (16%) isolates were found to be resistant against INH and one strian (2%) was found to be resistant against both RIF and INH. No strain was found to be resistant against RF alone. The present study revealed the presence of 2-3% of multi-drug resistant M. tuberculosis infection in patients attending DR. PSIMS general hospital. This emphazises the need for strengthening laboratory services for timely diagnosis of MDR TB. Keywords: Pulmonary tuberculosis, drug susceptibility, proportion method, Isoniazid. Rifampicin
Authors and Affiliations
Dr. M. Giridhar Kumar, Dr. Vishuvardhana Rao. K, Dr. C. R. Setty
Keywords
Related Articles
- EP ID EP374683
- DOI -
- Views 81
- Downloads 0
Awareness, Ownership and Utilization of Insecticide Treated Nets among Households in a Rural Community in Southern Nigeria
The use of Insecticidal Treated Nets (ITNs) is a key strategy for achieving a reduction in the malaria burden in Nigeria and other malaria endemic countries. This study was conducted to assess the awareness, ownership an...
Comparison between Combined Supraclavicular-Interscalene Block versus Interscalene Block Under Ultrasound Guidance in Patients Undergoing Humerus Shaft Fracture Surgery
Abstract: Fractures of proximal upper extremity present a challenge to the anaesthesia provider when administering a regional anaesthetic because the dermatomal distribution of the upper extremity requires more local ana...
Lower Lung Field Tuberculosis: A Clinical Study from Tertiary Care Teaching Hospital of North Karnataka
Pulmonary tuberculosis in the adult may present with unusual X-ray patterns that may lead diagnosis in the direction other than tuberculosis. This one year prospective study was designed to identify its prevalence in dif...
Clinically Amyopathic, PoikilodermatousDermatomyositis in a Male Child: Sporadic presentation of an otherwise common entity in a dermatology set-up
Abstract: Dermatomyositis is classified as an idiopathic inflammatory myopathy, mainly affecting the skin and the skeletal muscle; with a peak incidence in 5th-6th decade of life and twice as high in females. We present...
Ultrasonographic Evaluation of Gynecological Pelvic Masses - An Observational Study
Abstract: Pelvic ultrasound is commonly used as part of the routine gynecologic exams, resulting in diagnosis of adnexal masses, the majority of which are functional or benign. However, due to the possible complications...