STUDY OF PROTHROMBIN TIME (PT) AND CYTOGENETIC CHANGES IN PATIENTS WITH HBV IN WASIT PROVINCE
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 10
Abstract
Viral hepatitis type B is a disease caused by entry of hepatitis B virus (HBV) to the body, reaching the liver, multiplication, and stimulates the patient's immune system to attack the infected cells therefore caused inflammation of hepatocytes. The study included 40 blood samples from patients with HBV compared with 25 blood samples from control. Patients were divided according to their age into two groups. Levels of prothrombin time (PT) was measured and cytogenetic tests: mitotic index (MI), micronucleus assay (MN) and nuclear division index (NDI) were measured for patients lymphocyte. The study showed a significant increase (P<0.05) in prothrombin time of the patients when compared with control to all age groups, as well as the results of mitotic index, micronucleus assay and nuclear division index were significantly increasing (P<0.05) indicates a defect in cells division.
Authors and Affiliations
Dr. Kadhum J. Gattia
Keywords
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- EP ID EP674297
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