STUDY OF PROTHROMBIN TIME (PT) AND CYTOGENETIC CHANGES IN PATIENTS WITH HBV IN WASIT PROVINCE
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 10
Abstract
Viral hepatitis type B is a disease caused by entry of hepatitis B virus (HBV) to the body, reaching the liver, multiplication, and stimulates the patient's immune system to attack the infected cells therefore caused inflammation of hepatocytes. The study included 40 blood samples from patients with HBV compared with 25 blood samples from control. Patients were divided according to their age into two groups. Levels of prothrombin time (PT) was measured and cytogenetic tests: mitotic index (MI), micronucleus assay (MN) and nuclear division index (NDI) were measured for patients lymphocyte. The study showed a significant increase (P<0.05) in prothrombin time of the patients when compared with control to all age groups, as well as the results of mitotic index, micronucleus assay and nuclear division index were significantly increasing (P<0.05) indicates a defect in cells division.
Authors and Affiliations
Dr. Kadhum J. Gattia
Keywords
Related Articles
- EP ID EP674297
- DOI -
- Views 165
- Downloads 0
ASSESSMENT OF SOME BIOCHEMICAL PARAMETERS AMONG SMOKERS
This study was designed to evaluate the serum levels of creatinine, urea and activities of Alkaline phosphatase (ALP), Gamma glutamyl transferase (GGT), Creatine kinase (CK) and Lactate dehydydrogenase (LDH) among cigare...
EFFECTS OF EVACUATION SIGN IN A MAZE UTILIZING VIRTUAL REALITY (VR) ON BRAIN WAVES
This study aimed to develop an evacuation sign to ensure people quickly find an exit in smoke and darkness in the early stage of fires, and to measure changes in brain waves in the four areas of the cerebrum (frontal, pa...
CLINICAL AND IMMUNOLOGICAL FEATURES OF PATIENTS WITH CHD ASSOCIATED WITH TNF-A
The study included 101 patients with coronary heart disease aged from 34 to 76 years (56.9 ± 0.9), of them 64.4% were men and 35.6% - women. We have shown the role of TNF-α gene (-308G> A) in the development of CHD-allel...
BREASTFEEDING AND ASSOCIATED WITH ASTHMA AMONG CHILDREN IN BAGHDAD
Background: Breast feeding is the ideal method for infant's nutrition, is considered as the first immunization dose which can protected the infant from several diseases. Aims: to describe the association between breastfe...
WHIPPLE’S DISEASE: WHAT IS KNOWN AND WHAT IS NEW
Whipple’s disease is a rare chronic bacterial infection with a multi systemic pattern, due to Tropheryma whipplei. It occurrs in subjects with cell-mediated immunity defects. It generally begins with a recurrent joint le...