Study of rabies and development of preparations and methods of its prevention in the Republic of Belarus
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2018, Vol 33, Issue
Abstract
Introduction. Rabies is an absolutely deadly acute viral disease that affects a person and all warm-blooded animals, which is common in many countries of the world, including in Belarus. Due to its socio-economic importance, it occupies one of the leading places in infectious pathology, and therefore, an extremely important attention is given to its study, development of prevention and control measures. The goal of the work. Conduct an analysis of existing and determine the prospects for future developments in the field of means and methods of preventing rabies of wild carnivores. Results of research and discussion. The results of studying of rabies in Belarus on the basis of the State Institution “RSPC of Epidemiology and Microbiology” and RUE “Institute of Experimental Veterinary named of S.N. Vyshelessky”. The data of researches in the field of epizootology and epidemiology of rabies in the Republic, pathogenesis and improvement of diagnostics are presented. Particular attention was paid to the development of rabies vaccines and the method of oral vaccination of wild carnivores against rabies. Conclusions and prospects for further research. As a result of conducted researches by the employees of “Institute of Experimental Veterinary named of S.N. Vyshelessky” a liquid culture inactivated rabies vaccine “BELRAB”, the vaccine “Rabirif” for post-exposure prophylaxis of rabies, polyvalent vaccines against rabies, parvovirus enteritis, distemper and infectious hepatitis of carnivores were developed. A highly biologically active vaccine rabies virus (KMIEV-94 strain) was selected, the technologies of its suspension cultivation in BHK-21/13 cell culture and producing of oral vaccine blister packs were developed.
Authors and Affiliations
Yuriy Lomaka, Nikolai Kovalev, D. V. Buchukuri, Dmitry Borisovets, T. A. Zuykevich
Keywords
Related Articles
- EP ID EP410094
- DOI 10.31073/vet_biotech33-10
- Views 82
- Downloads 0
Determination of acute toxicity parameters and improving the effect of utero-tonic preparation “Uterodev”
Introduction. The designed new injectable preparation “Uterodev” recommended for the stimulation of labor activity, atony and hypotension of the uterus, prophylaxis of postpartum complications (postponement delay, MMA sy...
The results of serological test of cattle for chlamydiosis in Ukraine in 2016–2018
Introduction. Chlamydiosis of animals is infectious diseases of mammals and birds caused by Chlamydia. The disease causes significant economic losses, that why the disease is actual problem for veterinary medicine in cou...
Cellular prion level in the animals’ tissues
Prion infections cause brain damage in humans and animals with lethal outcome. Cellular prion (PrPC) is a precursor of pathological prion. Infection development depends on the level of its production in the different tis...
Validation of the method for determining histamine in fish and fish products by the method of liquid chromatography using an uv detector and derivatization
Introduction. Histamines are biogenic amines that are formed in fish and fish products during the decarboxylation of histidine with the involvement of enzymes that produce microflora with impaired storage conditions. His...
Phagocytosis and sockets forming activity of neutrophils in the latent course of equine infectious anaemia
Introduction. One of the important problems in horse breeding is infectious anemia, which is constantly registered in many countries. Pathogen is a retrovirus, morphologically similar to bovine leukemia virus. Basic mech...