Study of Relationship between Plasma Homocysteine Levels and Gestationalhypertension
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
A case control study comprising of 111 participants with 50 cases and 61 controls was performed. A fasting sample of plasma homocysteine was obtained from all the cases and controls. Plasma homocysteine was measured using the Chemi luminescence immunoassay method. It was found that the mean plasma homocysteine levels were higher in hypertensive women and increased with severity of disease. If there was positive family history of cardiovascular disease then plasma homocysteine levels were found to be higher. Higher the SBP, DBP & MAP values, higher were the levels of plasma homocysteine.Thus the study establishes the positive relationship between plasma homocysteine levels and gestational hypertension. Increased levels of plasma homocysteine in pregnant women could be used as a potential marker for predicting gestational hypertension and its severity.
Authors and Affiliations
Dr. V. Geetha, Dr. P. Thilagavathy
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