Study of rise of intraocular pressure and effect onvisual outcome in patients receiving intravitreal triamcinolone acetonide in macular disorders
Journal Title: Medpulse International Journal of Ophthalmology - Year 2019, Vol 9, Issue 1
Abstract
Background: Macular edema represents a final common pathway response of the retina to a variety of possible insults. Intravitreal triamcinolone acetonide is commonly used in treatment of macular edema and hence complications associated with the treatment especially rise of IOP is common.Purpose:To find out the effect of Intravitreal injection of Triamcinolone Acetonide on IOP and visual outcome in various macular disorders.Materials and methods: It was a hospital based, prospective, non-randomised case study of 30 eyes of 30 patients receiving IVTA injections over duration of 1 year.Results: The mean pre-injection IOP was 14mmhg [11.7-16.3 mmHg]. The mean IOP at the end of 1 day, 1 week, 1 month and 3 month was 15.43mmhg, 17.53mmHg, 18.50mmhg and 16.40mmhg, respectively, with a maximum percentage change from the initial occurring at 1 month [31.9%]; the changes found to be significant. Majority [22 out of 30] of the patients in this study experienced a rise in IOP from baseline of upto 3-6 mmHg. The patients who experienced 3-6mmHg rise in IOP from baseline at 3 months follow up were treated with adequate control of IOP.In our study, there was significant improvement in visual acuity [Snellen’s acuity improved by >/2lines] at the end of 1 and 3 months when compared with the initial visual acuity and visual acuity at the end of 1 week [ p-value<0.001]. Conclusion:Intravitreal Triamcinolone Acetonideresults in a significant rise in IOP which returns to initial baseline values within 3months of receiving treatment. Intravitreal Triamcinolone Acetonide results in a significant improvement in BCVA in patients diagnosed to have non-resolving macular oedema as a consequence of vascular and occlusive diseases of the retina
Authors and Affiliations
Latha C, Bhagya M
Keywords
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