Study of serum level of Vit. E, Malondialdehyde(MDA) and reduced glutathione(GSH) in RA patients & Comparison with normal subjects
Journal Title: Scholars Academic Journal of Biosciences - Year 2016, Vol 4, Issue 5
Abstract
Abstract:Rheumatoid arthritis (RA) is a chronic disease with unknown etiology. The aim of this study to estimate the serumVit.E,Malondialdehyde(MDA) and Reduced glutathione (GSH) in RA patient and comparison with normal healthy subjects. In the study the serum level of vit.E was estimated by method given by Catignani & Bieri.Serum MDA is estimated by a thiobiteric acid assay method and serum GSH were determined by the method of Paglia and Valentine. Serum level of Vit.E and Reduced glutathione were significantly reduced in RA patient as compared to control group (p <0.005 for Vit.E and p< 0.005 for GSH). Serum MDA level in RA patient was significantly higher than control group. Keywords:Rheumatoid arthritis (RA), Vit.E, Malondialdehyde (MDA), reduced glutathione (GSH), Super oxide dismutase (SOD), Catalase, glutathione peroxidase.
Authors and Affiliations
Sharma Virendra, Upadhyay Nisha, Yadav Kavita
Keywords
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