Study of serum testosterone level in males with Prediabetes, before and after 3 months of metformin therapy, in patients attending a tertiary care hospital in West Bengal, Eastern India
Journal Title: Journal of Medical Science And clinical Research - Year 2019, Vol 7, Issue 1
Abstract
Introduction: Hypogonadism is common in diabetes and prediabetes both. Metformin ,insulin sensitiser, is approved therapy for prediabetes Aim of the study: to assess whether metformin has any effect on serum testosterone level or not in males with prediabetes Materials and Methods: 48 males with prediabetes participated in the study .They were divided in two groups -Group A with baseline serum testosterone level more than 300 ng/dl and Group B with baseline serum testosterone level less than 300 ng/dl. Their testosterone levels were re-evaluated after 3 months of metformin therapy Result: Prediabetes men in hypogonadal group showed significant improvement in serum testosterone level. Both groups participants had improvement in erectile dysfunction Conclusion: metformin therapy in prediabetes male also helps in improvement of testosterone level
Authors and Affiliations
Neeraj Sinha
Keywords
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