Study of serum zinc level in overt and subclinical hypothyroidism – A case control study
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction Hypothyroidism is a clinical condition which is characterized by low thyroid hormone synthesis It results in slowdown of metabolic processes and also presents with biochemical abnormalities including reduced serum zinc levelObjectives This study was done to estimate the serum zinc level in subclinical and overt hypothyroidism casesMaterials and Methods Study included 90 patients of hypothyroidism of which 60 subclinical and 30 overt cases and 91 age sex matched healthy controls Venous blood was used for testing serum fT3 fT4 TSH and zinc levels Statistical analysis was done using student t test Pearsons correlation between serum zinc and thyroid parameters was used to establish the relationshipResults The serum zinc levels were significantly decreased in subclinical and overt hypothyroidism cases compared to controls and it showed significant negative correlation with TSHConclusion Serum zinc level is decreased in both subclinical and overt hypothyroidismKeywords fT3 free triiodothyronine fT4 free tetraiodothyronine TSH thyroid stimulating hormone Subclinical hypothyroidism Overt
Authors and Affiliations
Mahantesh B. Bhutal, Sangappa V. K, Shankarprasad D. S
Keywords
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- EP ID EP475199
- DOI 10.18231/2394-6377.2018.0093
- Views 61
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