STUDY OF THE BASELINE WIDAL TITRES AMONG HEALTHY INDIVIDUALS OF RURAL POPULATION IN PUDUCHERRY
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 2
Abstract
Background: Enteric fever is endemic in developing countries like India. Widal test in a single serum sample is often the only test relied upon for laboratory diagnosis. The test is considered positive if the antibody titres are higher than the cut - off value in a single test or a rising titre in paired sera. But normal baseline titres in healthy population and cutoff values have not been established in our area. So the aim of our study was to determine the base line titres of antibodies among apparently healthy populations and to define the significant titres of widal test. Materials and Methods: Samples were initially screened by Widal slide agglutination test and further confirmed by the Quantitative tube agglutination test. Results: Among the 500 samples from apparently healthy individuals, 260 samples were positive for agglutinins. 141 were positive for ‘O’ agglutinin and 163 were positive for ‘H’ agglutinin of Salmonella typhi. Among 141 samples, 30 showed agglutination up to 1in 20 titre, 100 up to 1in 40 and 25 (4.8%) up to 1in 80. Among 163 samples, 18 showed a titre of 1 in 20, 120 showed a titre of 1 in 40 and 21(4.2%) up to 1 in 80. Conclusion: When a single widal titre is used for the diagnosis of enteric fever in our locality, it will be more appropriate to change the currently used cutoff levels against S.typhi to ≥ 1 in 160 for anti-O and ‘H’ agglutinins remains the same of ≥ 1 in 160.
Authors and Affiliations
Jeyakumari D| Department of Microbiology, Tagore Medical College & Hospital, Chennai, Tamil Nadu, India, Corresponding author email: karailabscuddalore@yahoo.co.in, Jaberlin Sneha AJ| Department of Microbiology, Sri Manakula Vinayagar Medical College & Hospital, Puducherry, India, Gopal R| Department of Microbiology, Sri Manakula Vinayagar Medical College & Hospital, Puducherry, India
Keywords
Related Articles
- EP ID EP11394
- DOI 10.5958/2319-5886.2015.00060.0
- Views 230
- Downloads 11
A STUDY ON BEHAVIOURAL CHANGES INDUCED BY COLD WATER STRESS IN SWISS ALBINO MICE
Introduction: Stressful condition induces physiological and behavioral changes in an organism to maintain the normal homeostasis. The response to stress is regarded as a positive adaptive process of an organism, which...
Iranian key informants' perspectives towards gender sensitive STIs/HIV/AIDS prevention service delivery
More than 340 million new cases of sexually transmitted infections occur throughout the world every year. The average annual STIs growth rate was 17%from 1998 to 2006 in Iran. As this epidemic has progressed, relevant...
Investigating the Relationship of Organizational Commitment and Clinical Competence (Case study: Nurses Working in Montazeri Hospital, City of Najafabad, Iran, 2015)
Human resources committed to the organization not only reduces absence, delay, and replacement, but also causes the increase of organizational performance, employees’ mental freshness, better attainment to organizatio...
Comparison of Intubating Conditions with 0.6 mg/kg and 0.9 mg/kg Rocuronium Bromide for Rapid Sequence Intubation
Introduction: Dose of rocuronium bromide usually used for rapid sequence intubation (RSI) allows rapid paralysis but the duration of action is prolonged making it unsuitable for short duration surgeries. Theoretically,...
Comparison of Mec A Gene in Staphylococcus Aureus Isolated from Children at Time of Admission and Discharge in West of Iran
Staphylococcus aureus (SA) is a species of the genus Staphylococcus that is found everywhere, including in the respiratory tract and on the skin of many adults and children, and that is considered one of the main pathog...