Study of the clinico-etiological profile of fungal keratitis in a tertiary care hospital in North India
Journal Title: IP International Journal of Ocular Oncology and Oculoplasty - Year 2018, Vol 4, Issue 2
Abstract
Introduction Given the rise in cases of fungal keratitis in recent years this study was performed to better elucidate the clinical and microbiological profile risk factors and intervention rates of fungal keratitis at a tertiary referral center in UttarakhandMethods Corneal scraping was collected from 53 consecutive cases of suspected fungal keratitis and was subjected to direct staining and cultureResults This was a prospective observational study conducted over a period of 1 year after approval from the institutional ethical committee All the patients which appeared to be fungal or mixed keratitis on clinical examination were included in this study Out of 53 patients 37 698 were males and 16 302 females with a mean age of 4604 1623 years Maximum patients 18 3396 had the onset of symptoms and signs in the months of JulySeptember Of all the corneal ulcer which appeared fungal on clinical examination KOH and culture was positive in 509 patients While 189 were mixed type having both KOH and Gram stain positive Out of 53 patients 23 had presence of 3 or more typical clinical features of fungal keratits There was significant association between number of clinical features and KOH and culture positivity Fusarium and Curvularia species were the most common etiological agents in our regionConclusions Predominant outdoor agricultural activity and trauma with vegetative matter was the principal causative factor for corneal injury Corneal ulcers complicated due to prior treatment by village healers and hence another important concern The information regarding regional etiology will help empirical management as many eye clinics do not have microbiological facilitiesKeywords Cornea Fungal keratitis Microbiology
Authors and Affiliations
Prerna Upadhyay, Neeti Gupta, Harsh Bahadur, Aarti Kotwal
Keywords
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- EP ID EP513416
- DOI 10.18231/2581-5016.2018.0025
- Views 90
- Downloads 0
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