Study of thrombocytopenia in acute febrile illness and it’s prognostic significance at tertiary care hospital
Journal Title: Medpulse International Journal of Medicine - Year 2019, Vol 9, Issue 1
Abstract
Background: Febrile thrombocytopenia is a usually condition commonly caused by infections. India is a tropical country and a spurt in the number of cases of febrile thrombocytopenia has been noted, especially during the monsoon season. Objectives: To study the clinical profile and prognostic outcome of thrombocytopenia in acute febrile illness patients admitted in medicine ward. Material and Methods: A prospective study on 300 randomly selected cases presenting with acute febrile illness were selected after fulfilling inclusion and exclusion criteria’s. Detailed history was taken with preformed questionnaire. Appropriate laboratory investigations were done. Data was collected and analyzed using SPSS vs 20. Results: Dengue cases were found in majority with 143 (47.7%). Total of 101 (33.6%) cases had severely low platelets, most cases 169 (56.4%) belonged to moderate thrombocytopenia group. Dengue (71) was main etiology among 50,000 group, while viral fever (72) was major etiology in 50,000-1,00,000 group. Most common clinical presentations were rigors 72%, myalgia 67%, headache 44%. In 73% cases there were no any complications. Among 219 non complicated cases ARDS (12.7%) was most commonly seen. Out of total cases, 50 (6%) cases expired due to multiorgan failure. Severity of thrombocytopenia was significantly associated with death cases. Conclusions: Males forming greater burden, dengue being most common etiology in this study. Severity of thrombocytopenia was significantly associated with complication and death cases.
Authors and Affiliations
P T Gajbhare, A Agarwal, N Sutar
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