STUDY OF THYROID PROFILE BY USING ULTRA SENSITIVE 3 rd GENERATION THYROID ASSAY IN TYPE 2 DIABETES MELLITUS PATIENTS IN A TERTIARY CARE CENTER
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 8
Abstract
BACKGROUND Diabetes mellitus is a common endocrine disorder which is defined as a group of metabolic diseases characterized by hyperglycaemia resulting from defects in insulin secretion, insulin action, or both. Recently few studies have shown that Thyroid dysfunction especially hypothyroidism is found in patients with Type 2 Diabetes Mellitus but the mechanism for this is largely unknown. Unrecognized thyroid dysfunction can impair metabolic control in diabetes and may even exaggerate cardiovascular risk. Prompt detection and treatment may reduce risk derangement of cellular metabolism in diabetes mellitus and help achieving metabolic control in diabetes. AIMS AND OBJECTIVES OF THE STUDY To find the prevalence rate of thyroid disorders in type 2 diabetes mellitus by using 3rd generation thyroid assay and distribution of thyroid disorders in patients with Type 2 diabetes mellitus MATERIALS AND METHODS 150 patients diagnosed with type 2 diabetes mellitus or newly detected Type 2 diabetes mellitus without thyroid disorders attending outpatient departments and admitted to General medicine wards of Basaveshwar teaching and general hospital were included in this study. RESULTS Of the 150 patients with Diabetes 88 patients (58.66%) were male and 62 patients (41.33%) were male. The mean age in diabetic group 56.48±11.64 years. 84 patients (54%) in Diabetic group had hypertension and 25 patients (16.7%) diabetic group had coronary artery disease 43 patients (28.66%) had abnormal thyroid profile in diabetic group of which 23 patients (53.5%) had subclinical hypothyroidism and 16 patients (37.3 %) had overt hypothyroidism 2 (4.6) % patients had subclinical hyperthyroidism and 2 (4.6%) had overt hyperthyroidism. CONCLUSION The prevalence (28.8%) of thyroid dysfunction was common in type 2 diabetes mellitus patients. Our study shows significant co relation between abnormal thyroid profile and glycaemic control, dyslipidaemia and duration of diabetes.
Authors and Affiliations
Rahul Ladda, Sangram Biradar
Keywords
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- EP ID EP213600
- DOI 10.18410/jebmh/2017/83
- Views 90
- Downloads 0
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