Study of Thyroid Profile in Patients with Sepsis
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 12
Abstract
Background: Thyroid hormone abnormalities are frequently encountered in patients with sepsis, sepsis is important cause of death in developing countries. The aim of study is to analyze thyroid profile in sepsis patients at admission and evaluate the prognostic role of thyroid dysfunction in sepsis patients. Method: In prospective observational study, thyroid hormone levels (FT3, FT4, TSH) measured in 75 inpatients with sepsis . Serum thyroid level measured by chemiluminescent assay at the time of admission. Sepsis patients further divided into survivors and non- survivors. Observation and Results: Thyroid profile was assessed in 75 sepsis inpatients, low FT3 (56%) was the commonest abnormality observed, followed by low FT4 (10.67%) and high TSH (10.67%) followed by low TSH (8%). -Non survivors have low mean FT3 (1.56 ± 0.77) than survivors (2.31 ± 0.65) which was statistically significant (p <0.0001). Significant positive correlation observed between serum FT3 and serum albumin (p=0.002, r=0.36) Conclusion: low level of FT3 has positive correlation with decrease survival in sepsis patients. FT3 may be used as predictor of mortality. Serum FT3 and serum albumin have positive correlation.
Authors and Affiliations
A. Pal
A Study of Incidental Gall Bladder Carcinoma in Patients Undergoing Cholecystectomy at A Tertiary Care Hospital
Background: Gallbladder Carcinoma (GBC) is the most common malignancy of the biliary tract. It’s indolent and nonspecific clinical presentation and paucity of pathognomonic radiological features, often preclude diagnosis...
Hydatid Cyst in Lung- A Rare Case Report
Hydatid cyst is the cystic space occupying lesion caused by echinococcus .Cystic echinococcosis is a zoonosis caused by larval stage of E. granulosus .Other less common species are vogeli, oligarthrus, multilocularis. In...
Assessment of Blood Iron and Manganese on Artesant Welders Exposed to Welding Fumes
Whole blood iron and manganese levels in artesant welders control subjects were invstigated. Five (5ml) blood samples were collected via venepuncture from thirty (35) welders and twenty five (25) control subjects after t...
Intra Medullary Tuberculoma Presenting as Brown Sequard Syndrome with Concurrent Intradural Extramedullary Tuberculoma and Arachnoiditis
Intramedullary and intradural-extramedullary spinal tuberculomas causing spinal cord compression is an uncommon entity. We report an unique case of a 27-year-old Indian male patient on 4 drug antituberculous chemotherapy...
Evaluation of Thyroid Function Status in Patients with Chronic Kidney Disease
Chronic Kidney Disease is a worldwide health problem with an increasing incidence and prevalence. Abnormalities in the structure and function of the thyroid gland and in the metabolism and plasma concentration of thyroid...