Study of Vitamin D Level in Patient Presenting with Coronary Artery Disease
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Introduction: Coronary heart disease is common cause of morbidity and mortality worldwide. Vitamin D deficiency is common in general population, and is more prevalent among hospitalized patients. Vitamin D regulate cardiac contraction through its receptors in cardiac myocyte, and many studies support its role in acute myocardial infarction and heart failure. In this study, we seek to investigate the existence of an association between vitamin D and coronary heart disease in hospitalized patients. Material and Method: A case control study with 120 cases of coronary artery disease and 40 healthy controls was conducted. The standard clinical and biochemical risk factor for myocardial infarction were assessed in both cases and controls. Serum vitamin D assay was performed in cases and controls using radioimmunoassay technique. Observation: Vitamin D deficiency < 20 ng/ml was higher in cases (67%) than control (50%), with respect to this mean level was lower in case (18.96 ng/ml) and control ( 21.84 ng/ml) respectively. P value is < 0.0394. Conclusion: This study reveals high prevalence of vitamin D Deficiency in case and controls with level of 25 (OH) D being significantly lower among cases.
Authors and Affiliations
Dr P. Kukrele
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