Abstract

Objective: To study the anti-inflammatoryandanalgesic effects of FangXiangTongLuo-cervical Plaster. Methods: Preparation of FangXiangTongLuo cervical ointment. Using the model of the mouse ear swelling inflammation which is caused by xylene. The analgesic mode of hot-plate method and acetic acid wrinkle method, in order to study the anti - inflammatory and analgesic effects of FangXiangTongLuo-cervical Plaster. Result: The results showed that Fangxiangtongluo cervical plaster can effectively reduce the number of writhing in acetic acid-induced mice and increase the rate of writhing inhibition and analgesic percentage (p<0.01). In the hot plate experiment, Fangxiangtongluo cervical plaster can effectively improve the pain threshold of mice. With the increase in medication time, it can also significantly extend the time of the first mouse licking foot, thereby increasing the pain threshold of the mice. At the same time, Fangxiangtongluo cervical plaster can also significantly inhibit the degree of swelling of the mouse auricle caused by xylene, reducing the exudation of inflammatory substances in the body of mice. Conclusion: Fangxiangtongluo cervical plaster has significant anti-inflammatory and analgesic effects.

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