STUDY ON ANTIBACTERIAL EFFECTS OF SEVERAL VIETNAMESE MEDICINE PLANTS AND THEIR RELATIONSHIPS WITH POLYPHENOL CONTENTS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 4
Abstract
Objective: Our study evaluated the inhibitory effects of 13 plant materials on bacterial growth, so as to explain their traditional uses in bacterial infections. In addition, the correlation between antibacterial effects of plants and the polyphenol contents or antioxidant activities was also verified to investigate if these properties were responsible for the plant antibacterial effects. Methods: We tested extracts with 20 bacterial strains purchased from Japan Veterinary Products Association (JVPA, Tokyo, Japan) and also the Escherichia coli (E. coli) and Streptococcus suis (S. suis) strains that we had previously isolated from livestock. After polyphenol contents and antioxidant activities were measured, we examined their correlations with antibacterial effects. Results: The results showed that all extracts exerted inhibitory effects on tested bacteria and at different levels. Among all of samples, betel and mother rhizome of turmeric showed the strongest effects and also exerted inhibition on antibiotic-resistant E. coli and S. suis bacteria. In addition, direct and significant correlations between antibacterial effects’ and polyphenol content’s values were established and thus demonstrating that antibacterial effects of plants were attributable, at least in part, to the presence of polyphenol compounds. Conclusions: Our study demonstrated the antibacterial effects of 13 plant materials and, therefore, partly gives pharmacological basis to explain their traditional uses in diseases associated with bacterial infections. In addition, as betel and mother rhizome of turmeric showed the highest effects, we suggested that they might serve as the most promissory candidates for bacterial treatment. However, follow-up researches are still required to assess their potentials.
Authors and Affiliations
THANH VAN NGUYEN , HAI THANH NGUYEN
Keywords
Related Articles
- EP ID EP604689
- DOI -
- Views 114
- Downloads 0
MULTIVARIATE CALIBRATION TECHNIQUE FOR THE SPECTROPHOTOMETRIC QUANTIFICATION OF IVERMECTIN IN PHARMACEUTICAL FORMULATION
Objective: The present abstract makes the use of multivariate calibration technique for the quantification of ivermectin in pharmaceutical dosage form. Methods: Multivariate calibration technique is based on the use of...
PICA WITH AN UNUSUAL FORM OF PRESENTATION: A CASE REPORT
ABSTRACTGeophagia is a condition involving the consumption of mud and is a form of eating disorder known as pica. Pica is an unusual craving for ingestion ofeither edible or inedible substances. Although, pica is not lin...
FREE RADICAL SCAVENGING ACTIVITY OF VARIOUS EXTRACTS OF WHOLE PLANT OF Calycopteris floribunda (Lam.): AN IN-VITRO EVALUATION
 Objective: The present research was subjected to screen the free radical scavenging activity of various extracts of whole plant of Calycopterisfloribunda by different in-vitro models.Methods: The antioxidant activity w...
DETERMINATION OF BIOACTIVE COMPONENTS OF BARLERIA COURTALLICA NEES (ACANTHACEAE) BY GAS CHROMATOGRAPHY–MASS SPECTROMETRY ANALYSIS
Objective: The present investigation was carried out to determine the possible bioactive components of stem, root, and leaf of Barleria courtallica Nees using a gas chromatography–mass spectrometry (GC-MS).Methods: The...
ISOLATION AND HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY ANALYSIS OF CONDITIONAL AMINO ACIDS FROM THE FRESH LEAVES OF ALTERNANTHERA SESSILIS
Objective: The objective of the study was to isolate the conditional amino acids present in the fresh leaves extracts of Alternanthera sessilis and compare the isolated amino acids with amino acid standards. Method: The...