Study on Clinical and Neuroradiological Profile on Patients of Optic Neuritis in Central India
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6
Abstract
Introduction: Optic neuritis (ON) is an acute inflammatory disorder of the optic nerve. The disease is characterized by unilateral or bilateral acute diminuition of vision, often accompanied by periocular pain maximally associated with eye movements. The majority of cases are idiopathic in origin. This study was undertaken to evaluate the clinical, neuroradiological, electrophysiological profile on patients of optic neuritis in context of various studies. Materials: The study is an observational study. The study was carried out in OPD patients and admitted patients in department of medicine and department of Ophthalmology ,Gandhi Medical College, Bhopal and and associated Hamidia Hospital Bhopal (M.P.).Patients presenting with unilateral or bilateral diminuition of vision less than 4 weeks, presence of relative afferent pupillary defect, dyschromatopsia and normal or swollen optic disc on fundus examination were included in this study. Optic neuropathies like ischemic, toxic, hereditary, compressive and patients under age of 15 years were excluded from study. All patients were subjected to history, clinical examination, visual evoked potential (VEP), MRI brain with orbit. Observations: 75 eyes of 61 patients were examined. Mean age was 35.29 years .Female preponderance was seen(65.5%). All patients presented with diminuition of vision less than 4 weeks, and defective colour vision. Bilateral involvement seen in 14 patients (23%). Papillitis (58% of eyes) was most common fundus finding. Prolonged P100 latency was seen in 44 patients (72%) on VEP.MRI Brain showed intracranial demyelination in 23patients(38%).MRI Orbit showed abnormal findings in 77% patients Conclusions: Majority of patients of Optic neuritis of Central India presented with poor visual acquity. Papillitis is frequently seen in patients. Prolonged P100 latency is most common finding seen on VEP. Therefore, VEP, MRI Brain with Orbit is highly recommended in patients of ON for proper management. Clinical profile of ON in Central India patients is different from that seen in Western population.
Authors and Affiliations
Prof. Dr T. N. Dubey
Keywords
Related Articles
- EP ID EP288137
- DOI -
- Views 74
- Downloads 0
Early Brain Metastasis in a Case of Aggressive Renal Cell Carcinoma: A Case Report
Renal cell carcinoma (RCC) accounts for approximately 2% of malignancies worldwide with about 3,00,000 cases diagnosed per year and 1,00,000 deaths with the highest incidence occurring in Western countries.[1]Brain metas...
Various Clinical Presentations of Nystagmus: Case Series and Review of Literature
Introduction: Nystagmus is a rhythmic regular oscillation of the eyes. In this case series, we present four cases who presented to the emergency department different clinical complaints and had nystagmus on examination....
Low Cost Innovative Modification of Vacuum Assisted Wound Therapy
Management of acute and chronic wounds constitute a significant workload and financial burden for health care organizations and also has a negative impact over the quality of life of patients. Successful management of th...
Upper Extremity Deep Vein Thrombosis (Paget –Von Schroetter Syndrome) - A Rare Case Report
Primary "spontaneous" upper extremity deep vein thrombosis is uncommon and is defined as thrombosis of the deep veins draining the upper extremity due to anatomic abnormalities of the thoracic outlet causing axillosubcla...
A Prospective Study to Assess the Role of Delta Np63 as a Molecular Marker in Blood for Early Diagnosis of Esophageal Squamous Cell Cancer at a Tertiary Care Centre in North India
Esophageal carcinoma is one of the deadliest cancers with highly aggressive potency, ranking as the sixth most common cancer among males and ninth most common cancer among females globally. Due to metastasis and invasion...