Study on Clinical Evaluation of Solitary Thyroid Nodule and its Correlation with Cytology and Histopathology

Journal Title: New Indian Journal of Surgery - Year 2017, Vol 8, Issue 3

Abstract

Aim of the Study: To evaluate solitary thyroid nodules clinically, to study the role of FNAC in these lesions, and to correlate clinical findings with cytology and histopathology. Materials and Methods: This was a prospective study done over a period of two years, in the department of General Surgery, Kakatiya Medical College, MGM Hospital, Warangal, Telangana. A total of 110 patients were included in the study. Clinical examination, cytology and histopathology findings were correlated. Results: Age of the patients ranged from 11 to 68 years and the male to female ratio was 1:2.6. Majority of cases were seen in the fourth decade. After comparison of results of FNAC with histopathology, FNAC showed overall diagnostic accuracy of 89.8% with specificity of 100%, sensitivity of 50% for malignant lesions, positive predictive value of 100 % for malignancy and negative predictive value of 88.7%. Conclusion: Solitary thyroid nodules are more common in the fourth decade of life and have a female preponderance. Fine needle aspiration cytology of these lesions has a good overall diagnostic accuracy of almost 90% but is less sensitive in detecting malignant lesions. FNAC is a very useful procedure for assessment of solitary Thyroid nodules especially in conjunction with complete clinical evaluation whenever a malignancy is suspected.

Authors and Affiliations

Koorapati Ramesh

Keywords

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  • EP ID EP472059
  • DOI 10.21088/nijs.0976.4747.8317.10
  • Views 68
  • Downloads 0

How To Cite

Koorapati Ramesh (2017). Study on Clinical Evaluation of Solitary Thyroid Nodule and its Correlation with Cytology and Histopathology. New Indian Journal of Surgery, 8(3), 358-363. https://europub.co.uk/articles/-A-472059