STUDY ON COMPARISON OF THE EFFECT OF TOPICAL INSULIN WITH NORMAL SALINE DRESSING IN HEALING OF DIABETIC FOOT ULCERS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 39
Abstract
BACKGROUND Numerous topical medication and gels are promoted for ulcer care and healing. Relatively, few have proved to be more efficacious than saline wet-to-dry dressings. The present study was aimed to compare the effect of topical insulin and normal saline dressing in healing of diabetic foot ulcers. MATERIALS AND METHODS The present two-year hospital-based randomised-controlled trial was conducted in the Department of General Surgery, Rangaraya Medical College, Kakinada, from April 2015 to March 2017. A total of 60 patients with diabetic foot ulcers were studied. Based on the envelop method, patients were divided into two groups of 30 patients each that is group A (topical insulin) and group B (normal saline). RESULTS In this males (66.67% in group A and 83.33% in group B) outnumbered females in both the groups with male-to-female ratio of 2:1 in group A and 4:1 in group B. The mean age in group A was 52.00 ± 11.00 years, and in group B, it was 57.00 ± 9.80 years (p=1.000). Among patients with group A, significant reduction of mean ulcer area was observed (307.23 ± 169.87 mm2 ) with higher mean percentage reduction (35.19 ± 19.00 percent), whereas in group B, the mean percentage reduction was significantly less (18.82 ± 4.06 percent) with less reduction of mean final ulcer area (149.90 ± 64.45 mm2 ) (p<0.001). CONCLUSION Overall, topical insulin dressing provided favourable outcome in patients with diabetic foot ulcer by significant reduction in wound area when compared to normal saline dressing and it had positive role in reducing the wound infection if present.
Authors and Affiliations
Chinnam Venkata Reddy, Satti Venkata Reddy, Penumala Amala, Bethi Ravi Kumar
Keywords
Related Articles
- EP ID EP219173
- DOI 10.18410/jebmh/2017/467
- Views 146
- Downloads 0
PIGMENTED ACTINIC KERATOSIS MASQUERADING AS MALIGNANT MELANOMA
PRESENTATION OF CASE A 28-year-old Asian, agriculturist by profession, presented to the Department of Ophthalmology with history of two pigmented lesions one each on the temporal and nasal bulbar conjunctiva of the right...
SINGLE STAGE VENTRAL ONLAY BUCCAL MUCOSAL GRAFT URETHROPLASTY BASED ON TUNICA VAGINALIS FLAP FOR BALANITIS XEROTICA OBLITERANS RELATED URETHRAL MEATAL AND NAVICULAR FOSSA STRICTURES
BACKGROUND Balanitis Xerotica Obliterans (BXO), also known as lichen sclerosus of penis is a chronic, progressive disease of the glans and prepuce that leads to phimosis and stricture of the urethra that can extend from...
INFLUENCE OF BODY MASS INDEX ON DISTANCE AND TEMPORAL CHARACTERISTICS OF GAIT IN CHILDREN WITH SPASTIC DIPLEGIA HAVING JUMP GAIT
BACKGROUND One of the leading causes of motor disability in children is cerebral palsy. 1 Various abnormal patterns of gait are described in this population of children. Jump gait is one of the common gait patterns in ch...
RHINO SCLEROMA OF NASAL AND PARANASAL SINUSES: A RARE CASE REPORT
Rhinosleroma is a chronic destructive bacterial infection of the nose and upper respiratory airways, caused by klebsiella rhinoscleromatis. We report a case of 22 years old male, who presented with symptoms of nasal obst...
JOSHI'S EXTERNAL STABILISATION SYSTEM (JESS), FOR RECURRENT CTEV DUE TO IRREGULAR FOLLOW UP
BACKGROUND The incidence of congenital talipes equinovarus is approximately one in every 1000 live births. Most cases are sporadic in occurrence. Contractures or anomalies of the soft tissues exert further deforming forc...