Study on invasive histopathological features of papillary thyroid carcinoma with tall cell variant
Journal Title: Journal of Surgery : Concepts & Practice - Year 2023, Vol 28, Issue 6
Abstract
[Objective] To study the invasive histopathological features of papillary thyroid carcinoma(PTC) with tall cell variant(TCV). [Methods] A retrospective analysis of 19 170 cases of PTC in Ruijin Hospital, Shanghai Jiao Tong University School of Medicine from January 2018 to May 2023 was performed to analyze and the clinicopathological features between TCV-PTC group and classic PTC (cPTC) group. [Results] Pathological results showed 1 380 cases in TCV-PTC group and 15 578 cases in cPTC group. TCV-PTC had higher proportion and (or) mean value in patients' age, extraglandular invasion, nerve invasion, vascular invasion, maximum diameter of cancer focus, multifocality，lymph node metastasis and BRAF mutation, but the proportion of patients with coexistent Hashimoto's thyroiditis was lower than cPTC， and all results had significant difference (P<0.05). [Conclusions] Compared with the cPTC, TCV-PTC has stronger local invasive characteristics and lymph node metastasis rate, which provides the basis for the subsequent clinical treatment.
Authors and Affiliations
Zhenyu LIAO, Qiwu ZHAO, Jie KUANG, Zhuoran LIU, Hanxing SUN, Yue WANG, Weihua QIU, Xi CHEN, Jiqi YAN
Keywords
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- EP ID EP750925
- DOI 10.16139/j.1007-9610.2023.06.07
- Views 47
- Downloads 1
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