STUDY ON RELATIONSHIP BETWEEN HIGH SENSITIVITY CRP AND ANGIOGRAPHIC SEVERITY OF CAD
Journal Title: PARIPEX-Indian Journal of Research - Year 2017, Vol 6, Issue 6
Abstract
Objective: (A) To study the levels of hs-CRP in patients with angiographically documented acute coronary syndrome (ACS), chronic coronary artery disease (chronic CAD) (B) To compare angiographic stenosis and extent score with hs-CRP levels in patients with ACS and chronic CAD. Methods: A total of 80 patients who were admitted with the diagnosis of subjected to coronary angiography were included in this study. The quantitative hs-CRP levels were measured by immunoturbidometry method. Gensini scoring was performed to measure the stenosis score and extent score. Later, the levels of hs-CRP were compared with the stenosis and extent score in angiographically documented CAD. Data was analysed using Statistical Package for the Social Science (SPSS) Version 11.5 Results: There was statistically significant hs-CRP elevation in angiographically confirmed CAD patients . It was found that hs-CRP levels were much higher in acute coronary syndrome patients. The hs-CRP levels were found to be in direct proportion to extent score of coronary artery disease . Also, angiographic stenosis score was found to be higher in patients with higher hs-CRP levels . Conclusion: Significant correlation was observed between the extent of coronary artery disease and hs-CRP levels. Similarly hs-CRP levels were found to be higher in patients with higher degree of angiographic stenosis. This shows that hs-CRP levels have a correlation with the disease burden in CAD patients.
Authors and Affiliations
Elamaran Chidambaram, Nambirajan Jayabalan, Swaminathan Nagarajan, Ravishankar Ganapathy, Nisamudeen Kajamohideen
Keywords
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