Study on the distribution of ABO blood group in patients with pancreatic cancer
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 2
Abstract
Objective To investigate whether there is a correlation between the differences in ABO blood group distribution in patients with pancreatic cancer, and to evaluate the relative risk. Methods Patients with pathological diagnosis or discharge diagnosis of pancreatic cancer who underwent ABO blood group typing in our hospital from January 2017 to October 2021 were selected, and the blood group distribution of patients and the correlation were analyzed. Results There was a statistically significant difference between the pancreatic cancer group and the control group (P<0.05). The study showed that type A may be a relative risk factor for pancreatic cancer patients (χ2=42.44, P<0.001), and type B may play a protective role (χ2=16.28, P<0.01). Significant differences were found in distribution between different gender groups (χ2=64.35, P<0.05). The test results showed that type A may be a risk factor for pancreatic cancer in men (χ2=35.2, OR=1.7, 95%CI=0.59-1.02, P<0.001), and type O may play a protective role in pancreatic cancer(χ2=18.22, OR=0.6, 95%CI=0.25-0.32, P<0.01); type A may be a relative risk factor for female pancreatic cancer patients (χ2=7.06, OR=1.4, 95%CI=0.59-1.02, P<0.001), while type B may play a protective role (χ2=20.32, OR=0.5, 95%CI=0.32-0.43, P<0.01). In pancreatic cancer group, the risk factors of blood type A were higher than those of non-A group, and the protective effect of type B was significantly higher than that of non-B group. Conclusion The distribution of blood group and relative risk factors in pancreatic cancer patients suggest that A type is predominant; in the population with A blood group, more attention should be paid to early prevention and early treatment, so as to reduce the risk of disease.
Authors and Affiliations
Xiaoliang YANG, Xiaoqin ZHOU, Jing LI, Xia ZHONG, Kun WANG, Xiaoyan TANG, Xing GU
Keywords
Related Articles
- EP ID EP738488
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.02.014
- Views 24
- Downloads 0
Application of traditional teaching combined with PBL in the teaching of transfusion medicine——taking Clinical Blood Transfusion Testing Technique as an example
Objective To explore the application effect of traditional teaching combined with problem based learning (PBL) in the teaching of transfusion medicine taking the chapter of Human Leukocyte Antigen System and Testing in C...
Clinical manifestations and genetic mutation analysis of 20 patients with congenital Fibrinogen disorders
Objective To retrospectively analyze the clinical manifestations, related laboratory examinations and gene mutation of 20 patients with congenital Fibrinogen disorders (CFD) admitted to our hospital from February 2017 to...
Meta analysis of the effect of pre-transfusion prophylactic medication on the incidence of adverse reactions to blood transfusion
Objective To systematically evaluate the correlation between pretransfusion prophylactic medication and the incidence of adverse reactions to blood transfusion(ARBT) by Meta analysis. Methods The relevant literature conc...
Determination of fibrinogen content in cryoprecipitated antihemophilic factor by fluorescence quenching method
Objective To establish a new method for the determination of fibrinogen content in cryoprecipitated antihemophilic factor. Methods Fibrinogen (Fib) could bind with sheep anti-human fibrinogen (anti-Fib) specifically and...
Comparison of effects of different anticoagulants on the release of growth factor and injection pain of platelet-rich plasma in SD rats
Objective To investigate the effects of different anticoagulants on platelet-rich plasma(PRP) release content of growth factor and injection pain. Methods A total of 15 voluntary blood donors were selected, with each blo...