Study on the production efficiency of platelet components in 24 prefecture-level blood stations in China
Journal Title: Chinese Journal of Blood Transfusion - Year 2022, Vol 35, Issue 9
Abstract
Objective To learn the production efficient of platelet components among prefecture-level blood stations in China, to provide supporting data for those blood stations to optimize the production mode of platelet components and continuously improve production efficiency and supply capacity. Methods The data from 2017 to 2020 was obtained from 24 prefecture-level blood stations who were the members of the practice comparison network for blood institutes in China. The collection units of apheresis platelets, the number of dual-collections of apheresis platelets and plasma, the average apheresis units of one platelet apheresis procedure, the discarded rate of apheresis platelets, the amount of expired apheresis platelets and the amount of apheresis platelets issued were collected. For concentrated platelets, the prepared amount of platelet concentrates and the amount of expired platelet concentrates were collected; both the quantity of qualified and issued concentrated platelets were submitted for statistical analysis.The total output and efficiency of platelet components were calculated based on the collected data. Results The average annual growth rate of apheresis platelets collection in 24 prefecture-level blood stations was 12.23%, accounting for 99.80% of the total platelet output; the average collection unit of one platelets apheresis procedure was 1.75; from 2019 to 2020, only 5 blood stations performed dual-collection of platelet and plasma during one apheresis procedure; the discarded rate of apheresis platelets was 0.28%, of which 0.007% was due to expiration. A total of 1 621.2 therapeutic units of concentrated platelets were prepared, and 13.03% of them was discarded due to the expiration. The production efficiency of platelet components was 97.56%, of which the production efficiency of apheresis platelets was 97.61% and the production efficiency of concentrated platelets was 74.43%. Conclusion There are large regional differences in the supply capacity of platelet components in prefecture-level blood stations. Apheresis platelets are the main resource of platelet components product, and the collection capacity is increasing over the years with the characteristics of high production efficiency and low expiration scrapping rate. However, the preparation of concentrated platelets are still limited with relatively low production and high expiration discarded rate.
Authors and Affiliations
Minyu HUA, Wei NIU, Jian YAO, Shouguang XU, Yuxia QIU, Li LI, Dongmei ZHAO, JiaYu WAN, Feng YAN, Hongzhi JIA, Hao LI, Jiaqi QiIAN, Peng WANG, Zhenxing WANG, Lin BAO, Shan WEN, Sheng YE, Xuefang FENG, Man ZHANG, Xiaobo CAI, Wei Zhang, Dexu CHU, Youhua SHEN, Peifang CONG, Hui ZHANG, Yan QIU
Animalexperiment on regulating effect of stored red blood cells transfusion on BMDMs in inflammatory conditions
Objective To discuss the regulating effect of stored red blood cells (RBCs) transfusion on BMDMs in inflammatory conditions, and the relationship between stored RBCs transfusion and inflammatory response induced by bacte...
Molecular mechanism and bioinformatics analysis of 9 samples with rare RhD variants
Objective To study the molecular mechanism of 9 samples with rare RhD variants and their RhD epitopes and protein structure. Methods The 9 blood samples with rare RhD variants were collected from 210 644 blood donors of...
Study on the ratio of blood transfusion components in disseminated intravascular coagulation caused by sever postpartum hemorrhage
Objective To investigate the transfusion ratio of plasma to RBC suspension during DIC caused by sever postpartum hemorrhage, so as to improve the clinical blood transfusion protocol. Methods A total of 82 parturients, wh...
Donor haemovigilance: retrospect and prospect
Donor haemovigilance (DHV) is one of the main contents of haemovigilance. In recent years, great progress has been made in improving DHV regulations and standards, establishing and developing DHV systems and promoting bl...
Establishment of platelet donor gene bank involving specific antigen HPA 1-6/10/15/21 by real-time fluorescent PCR
Objective To research the genetic polymorphism of HPA 1-6/10/15/21 in platelet donors in Zhongshan area, and establish a gene bank of platelet donors with HPA locus. Methods The HPA 1-6/10/15/21 system genotyping was per...