Study on the production efficiency of platelet components in 24 prefecture-level blood stations in China
Journal Title: Chinese Journal of Blood Transfusion - Year 2022, Vol 35, Issue 9
Abstract
Objective To learn the production efficient of platelet components among prefecture-level blood stations in China, to provide supporting data for those blood stations to optimize the production mode of platelet components and continuously improve production efficiency and supply capacity. Methods The data from 2017 to 2020 was obtained from 24 prefecture-level blood stations who were the members of the practice comparison network for blood institutes in China. The collection units of apheresis platelets, the number of dual-collections of apheresis platelets and plasma, the average apheresis units of one platelet apheresis procedure, the discarded rate of apheresis platelets, the amount of expired apheresis platelets and the amount of apheresis platelets issued were collected. For concentrated platelets, the prepared amount of platelet concentrates and the amount of expired platelet concentrates were collected; both the quantity of qualified and issued concentrated platelets were submitted for statistical analysis.The total output and efficiency of platelet components were calculated based on the collected data. Results The average annual growth rate of apheresis platelets collection in 24 prefecture-level blood stations was 12.23%, accounting for 99.80% of the total platelet output; the average collection unit of one platelets apheresis procedure was 1.75; from 2019 to 2020, only 5 blood stations performed dual-collection of platelet and plasma during one apheresis procedure; the discarded rate of apheresis platelets was 0.28%, of which 0.007% was due to expiration. A total of 1 621.2 therapeutic units of concentrated platelets were prepared, and 13.03% of them was discarded due to the expiration. The production efficiency of platelet components was 97.56%, of which the production efficiency of apheresis platelets was 97.61% and the production efficiency of concentrated platelets was 74.43%. Conclusion There are large regional differences in the supply capacity of platelet components in prefecture-level blood stations. Apheresis platelets are the main resource of platelet components product, and the collection capacity is increasing over the years with the characteristics of high production efficiency and low expiration scrapping rate. However, the preparation of concentrated platelets are still limited with relatively low production and high expiration discarded rate.
Authors and Affiliations
Minyu HUA, Wei NIU, Jian YAO, Shouguang XU, Yuxia QIU, Li LI, Dongmei ZHAO, JiaYu WAN, Feng YAN, Hongzhi JIA, Hao LI, Jiaqi QiIAN, Peng WANG, Zhenxing WANG, Lin BAO, Shan WEN, Sheng YE, Xuefang FENG, Man ZHANG, Xiaobo CAI, Wei Zhang, Dexu CHU, Youhua SHEN, Peifang CONG, Hui ZHANG, Yan QIU
Keywords
Related Articles
- EP ID EP738347
- DOI 10.13303/j.cjbt.issn.1004-549x.2022.09.013
- Views 49
- Downloads 0
Study on the hepatitis B virus infection in blood donors reactive to jointed NAT but non-reactive to primary discriminatory test
Objective To analyze the status of HBV infection in blood donors reactive to jointed NAT but non-reactive to primary discriminatory tests (NRR), so as to provide suggestions and data support for subsequent studies on NRR...
Application of intelligent information system of transfusion reactions in the supervision and management of transfusion reactions
Objective To analyze the application effect of intelligent information system of transfusion reactions(referred to as the system) in the supervision and management of transfusion reactions. Methods A retrospective analys...
Optimization of large-scale production process for human prothrombin complex concentrates
Objective To determine the optimal process conditions for efficiently extracting human prothrombin complex concentrates from human plasma. Methods Using human plasma as the materials and the yield of prothrombin complex...
Molecular mechanism of circRNA hsa_circ_0000290 regulating Zika virus replication: a preliminary study
Objective To investigate the effect of transfusion-transmitted Zika virus (ZIKV) on the expression of circular RNA (hsa_circ_0000290) and the role of hsa_circ_0000290 in ZIKV replication. Methods A549 or U251 cells were...
The capacity evaluation and utilization strategy of the platelet donor database with known HLA/HPA genotype in Shaanxi
Objective To evaluate the appropriate optimal capacity and matching probability of the platelet donor database with known HLA/HPA genotype in Shaanxi aera, and provide data support for subsequent construction, maintenanc...