STUDYING THE ENZYMES LEVELS IN CEREBROSPINAL FLUID FOR CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2017, Vol 6, Issue 5
Abstract
The research includes studying of enzymes levels in the cerebrospinal fluid (CSF) for children with acute lymphoblastic leukemia (ALL) by determination of (9) parameter which include biochemical parameters: Acetylcholinesterase (AChE), Pseudocholinesterase (PChE), Monoamine oxidase A (MAOA), Aspartate aminotransferase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), Creatinine kinase (CK), Lactate dehydrogenase (LDH) and Superoxide dismutase (SOD). The study was done on (140) sample had acute lymphoblastic leukemia (95) were male and (45) female, beside of (73) were healthy children as control group which include (39) male and (34) female the age of children with acute lymphoblastic leukemia ranged from 1-15 year for both sex. The results showed there was a significant decrease in the activity of AChE, PChE and a significant increase in MAOA, AST, ALT, ALP, CK, LDH and SOD in CSF for children with acute lymphoblastic leukemia patients compared with control group for both sexes and these were a very good biochemical indicators for the patient body biochemical functions. The blood brain barrier loss its function in maintaining brain homoeostasis because of the oxidative stress and the age group (11-15)y of male had higher oxidative stress.
Authors and Affiliations
Dr. Lelas Farhan Bdaiwi
Keywords
Related Articles
- EP ID EP618158
- DOI -
- Views 138
- Downloads 0
ISOLATION OF PIGMENT PRODUCING HALOPHILIC BACTERIA FROM MARAKKANAM SALT PANS AND EVALUATION OF THEIR ANTIOXIDANT ABILITY
Halophilic organisms are a type of extremophiles that survive in the environment with very high salt concentration. In the current study, pigment producing halophilic bacteria was isolated from the salterns of Marakkanam...
AYURVEDIC PRINCIPLES OF EATING
Ayurveda, the science of healthful living, is the most rational and scientific among the ancient systems of medicine. Ayurveda has immense potential to tackle many medical problems. Agadtantra is the branch of Astangaayu...
ENZYMES ACTIVITIES & LIPID PROFILES AMONG PATIENTS WITH BREAST CANCER
Background: Breast cancer a multifactorial disease with its uncertain etiology remains as one of the most dreaded of human diseases that claims the lives of thousands of women all over the globe every year. This may prob...
TREND OF SPINAL CORD COMPRESSION SYNDROMES: AN ANALYSIS OF 529 CASES IN A TERTIARY HOSPITAL, IN NORTH-WESTERN NIGERIA
Background: Neurological disorders contributed to ninety two( 92) million Disability-Adjusted Life Years (DALYs) in 2005 and is projected to increase to 103 million in 2030. In view of this considerable morbidity associa...
PAPER RECYCLING PROCESS DEVELOPMENT
Paper is the major utility in modern world and highest amount of papers are used in daily life. Most of the paper are useless after using thorn way. It causes environmental pollution in some times. Today 90 % of paper co...