Sublingual Misoprostol as an Adjunct to Oxytocin During Cesarean Delivery in Women at Risk of Postpartum Hemorrhage
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 2
Abstract
Objective: To assess the efficacy of sublingual misoprostol as an adjunct to parenteral oxytocin in preventing blood loss during and after surgery in patients with high risk for postpartum hemorrhage. Method: One hundred seventy-five women who were high risk for postpartum hemorrhage and undergoing emergency cesarean delivery were assigned randomly to receive either 400 μg misoprostol or placebo sublingually at the time of cord clamping. All participants received an intravenous infusion of 20 units of oxytocin. The primary outcome measures were intraoperative and postoperative blood loss. Results: Mean intraoperative blood loss was significantly less in misoprostol group as compared with placebo group (595 ± 108 vs. 651 ± 118 ml, P = 0.025). Perioperative Hb fall was significantly less in misoprostol group (0.87 ± 0.29 vs. 1.01 ± 0.26 g, P = 0.0018). Conclusion: Misoprostol as an adjunct to oxytocin is more efficient in preventing blood loss as compared to oxytocin alone.
Authors and Affiliations
Cimona Lyn Saldanha, Shabnum Araujo, Umrazia Bashir
Keywords
Related Articles
- EP ID EP544826
- DOI 10.21276/ijmrp.2017.3.2.067
- Views 87
- Downloads 0
Assessment of Expression of Myofibroblast in Oral Submucous Fibrosis
Background: Oral Submucous fibrosis (OSMF) is an insidious, chronic disease affecting any part of the oral cavity and sometimes the pharynx. After tissue injury, fibroblasts differentiate into contractile and secretory m...
Outcome of Supracostal Puncture for Percutaneous Nephrolithotomy for Renal Stones: A Retrospective Analysis
Objective: Supracostal superior calyceal puncture is best puncture for staghorn, upper ureter, superior and inferior calyceal stone. The objective of this study is to analyzed the data from single centre regarding. The a...
A Need of Saudi Health Promotion Staff for Training on Diabetes Mellitus Health Care Literacy
Background: Diabetes mellitus is a burdening public illness in Saudi Arabia. Controlling diabetes needs multiple inter-professional actions. One of the important professional is health educator. Insufficient knowledge of...
A Prospective Study of Functional Outcome of Surgical Management of Ipsilateral Tibia and Femur Fracture (Floating Knee Injuries)
Background: Floating knee injuries are due to high velocity trauma. Due to increase in incidence of high velocity trauma their incidence is also increasing. The aim of this study to evaluated the functional outcome in pa...
Intuitive Medicine
In this present age of evidence-based medicine, the value of Intuition in medical practice is under-rated. Generally, it is regarded with indifference if not contempt. An experienced doctor will know the importance of an...