Successful En-Bloc Kidney Transplantation from a 5-year-Old Donor with Cerebral Palsy to a 60-Year Old Recipient: A Case Report

Journal Title: Translational Research in Urology - Year 2021, Vol 3, Issue 1

Abstract

Introduction There are a growing number of unmet kidney donor sources. So, alternative donor sources, such as donation after circulatory determination of death (DCDD), are taken into the consideration. Case presentation In this study, we represent successful En-Bloc kidney transplantation from a 4-year-Old donor with cerebral palsy to a 60-year old recipient. The kidney of a 4-year-old boy with congenital CP (weight=12Kg; BMI=12) with brain death was transplanted to a 60-year-old man (weight =70Kg; BMI=23.6). Panel-reactive antibody (PRA) to HLA class I (PRA I) and HLA class II (PRA II) were observed less than 5% in the 60-year old recipient. Also, the PRA titer with complement-dependent cytotoxicity (PRA-CDC) and the donor-recipient WBC crossmatch were negative. Our case is reported by a successful EKBT to an adult with the en-bloc kidney of a 4-year-old child with cerebral palsy. The small kidneys of a cerebral palsy child are adapting and functioning well in the adult body. Conclusions Therefore, CP pediatric donors can be good resources for transplantation whenever available.

Authors and Affiliations

Mohammad Hatef Khorrami, Sanaz Dehghani, Rahil Mashhadi, Hossein Abdi, Farshad Namdari

Keywords

Related Articles

Short term and Long term Survival Rate and Risk Factors of Graft Rejection after Deceased Donor Kidney Transplantation: A Systematic Review and Meta-Analysis

Introduction: The purpose of the current meta-analysis was to determine the short-term and long-term graft survival and patient survival from the deceased donors, and determine the prognostic factors. Methods: PubMed, S...

The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies

Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade. Aging of the population and Urbanization has induced...

The Two-Point Technique of Fluoroscopy during the Urological Procedure: Is Really Necessary?

Nowadays the common use of diagnostic and therapeutic ionizing radiation increases worries about excessive occupational and patient exposure. The novel fluoroscopic-guided endoscopic procedures can diminish radiation dos...

The Impact of Potassium Citrate on the Kidney Stones Treatment in Rat

Introduction: Nephrolithiasis is one of the most common prevalent diseases in the human population, with a high recurrence rate. Although the prophylaxis effect of potassium citrate in renal calculi is well known, its th...

Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones

Introduction: To assess the therapeutic efficacy of potassium citrate in the nonsurgical management of renal stones we run this research. The prophylactic effects of Potassium Citrate over renal stone formation have been...

Download PDF file
  • EP ID EP704073
  • DOI 10.22034/TRU.2021.257484.1049
  • Views 77
  • Downloads 0

How To Cite

Mohammad Hatef Khorrami, Sanaz Dehghani, Rahil Mashhadi, Hossein Abdi, Farshad Namdari (2021). Successful En-Bloc Kidney Transplantation from a 5-year-Old Donor with Cerebral Palsy to a 60-Year Old Recipient: A Case Report. Translational Research in Urology, 3(1), -. https://europub.co.uk/articles/-A-704073