Successful Intravenous Lipid Infusion Therapy in a Case with Life-Threatening Calcium Channel and Beta Blockers Overdose
Journal Title: Çocuk Acil ve Çocuk Yoğun Bakım Dergisi - Year 2016, Vol 3, Issue 3
Abstract
Life-threatening cardiovascular collapse symptoms can develop due to calcium channel and beta-receptor blocker overdose and there are no specific antidotes for treatment. A 13-year-old girl was admitted with severe hypotension and bradycardia after ingestion of an overdose carvedilol and verapamil. Cardiovascular collapse was resistant to fluid therapy, calcium gluconat and high-dose vasopressor infusion. Intravenous lipid infusion was administered in the patient who had resistant hypotension with hiperinsulinemic euglycemia on the first hour of hospitalization. Hemodynamic stability of the patient was achieved 30 minutes after lipid administration. Calcium channel and beta-receptor blocker overdose may result in life-threatening intoxication. Classical therapies suggested for these intoxications can be insufficient. Favorable results can be obtained after intravenous lipid infusion. With this report, we aimed to draw attention to those intoxications that can be life-threatening and emphasize that intravenous lipid infusion therapy can be successful in patients refractory to other treatments.
Authors and Affiliations
Fatih Durak, Fulya Kamit Can, Neslihan Zengin, İkbal Durak, Kerem Yıldız, Ayşe Berna Anıl
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