Successful Slow Induction of Tolerance to Co-Trimoxazole in HIV Positive Patient Cross Reactive to Co-Trimoxazole and Dapsone
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Abstract:Co-trimoxazole and alternatively Dapsone is used for chemoprophylaxis for opportunistic infection in HIV positive patients. Desensitization to Co-trimoxazole is attempted when there is no other alternative. Different desensitization protocols are studied abroad but Indian data are much scarce. The present case reports a 28 year old newly diagnosed treatment naïve HIV positive patient who was intolerant to NACO recommended protocol but induction of tolerance was successful when dose was up-titrated at a slower rate. Keywords:co-trimoxazole, cross-reactivity, dapsone, immunological desensitization, sulfa allergy
Authors and Affiliations
Sukalyan Saha Roy
Keywords
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