Suitable solvent and drying condition to enhance phenolics and extractive value of Saussurea costus
Journal Title: Journal of Ayurvedic and Herbal Medicine - Year 2016, Vol 2, Issue 5
Abstract
Plants are rich source of medicinally important compounds such as phenolics compounds and flavanoid used as antioxidant and have chemo-preventive role against the risk of oxidative stress-related diseases. Saussurea costus (Falc.) Lipsch. ( Asteraceae ) have medicinal properties, such as anti-inflammatory, antioxidant, hepatoprotective, antiulcer, anticancer, immunomodulatory and pesticidal activities. Phytochemical investigation was carried out with hexane, chloroform, methanol and ethanol extract. six extracting solvents, methanol, ethanol, aqueous methanol (80% v/v), aqueous ethanol (80% v/v), aqueous methanol (70% v/v) and aqueous ethanol (70% v/v) were applied for their efficacy to extract antioxidants from air-dried, sun-dried and oven-dried roots of Saussurea costus. There was a significant difference (P < 0.05) in the extracting ability of each of the solvents. The aqueous solvents were found superior in their ability to extract the antioxidants and aqueous ethanol was reported more efficient than aqueous methanol. Highest and lowest extractive value and antioxidants compounds were found from respectively Oven dried (40°C) and air dried (ambient, approx 25°C) Saussurea costus roots. There was an excellent correlation between extraction yield, antioxidant activity and total phenolic content.
Authors and Affiliations
Aziz Ahmed*, Sayeed Ahmad, Kirti Soni, Bhavana Lapa, Mohd. Afzal, Kazal Sharma, Gaurav Kumar
Keywords
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